| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M1 |
|---|
| Ligand | BDBM50006546 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_138935 |
|---|
| Ki | 18900±n/a nM |
|---|
| Citation |  Carroll, FI; Abraham, P; Chemburkar, S; He, XC; Mascarella, SW; Kwon, YW; Triggle, DJ Synthesis and muscarinic receptor activity of ester derivatives of 2-substituted 2-azabicyclo[2.2.1]heptan-5-ol and -6-ol. J Med Chem35:2184-91 (1992) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Muscarinic acetylcholine receptor M1 |
|---|
| Name: | Muscarinic acetylcholine receptor M1 |
|---|
| Synonyms: | ACM1_RAT | Cholinergic, muscarinic M1 | Chrm-1 | Chrm1 | cholinergic receptor, muscarinic 1 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 51390.46 |
|---|
| Organism: | RAT |
|---|
| Description: | P08482 |
|---|
| Residue: | 460 |
|---|
| Sequence: | MNTSVPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVN
NYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLIS
FDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYI
QFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSS
SERSQPGAEGSPESPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEV
VIKMPMVDSEAQAPTKQPPKSSPNTVKRPTKKGRDRGGKGQKPRGKEQLAKRKTFSLVKE
KKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTVNPMCYAL
CNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC
|
|
|
|---|
| BDBM50006546 |
|---|
| n/a |
|---|
| Name | BDBM50006546 |
|---|
| Synonyms: | Acetic acid 2-benzyl-2-aza-bicyclo[2.2.1]hept-5-yl ester | CHEMBL67700 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H19NO2 |
|---|
| Mol. Mass. | 245.3169 |
|---|
| SMILES | CC(=O)OC1CC2CC1CN2Cc1ccccc1 |TLB:3:4:10.9:7,11:10:4.5:7| |
|---|
| Structure | 
|
|---|
Search and Browse
