Reaction Details |
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Target | Sigma non-opioid intracellular receptor 1 |
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Ligand | BDBM50006983 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_201262 (CHEMBL804880) |
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IC50 | 7±n/a nM |
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Citation | Wilson, AA; Dannals, RF; Ravert, HT; Sonders, MS; Weber, E; Wagner, HN Radiosynthesis of sigma receptor ligands for positron emission tomography: 11C- and 18F-labeled guanidines. J Med Chem34:1867-70 (1991) [PubMed] |
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More Info.: | Get all data from this article, Assay Method |
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Sigma non-opioid intracellular receptor 1 |
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Name: | Sigma non-opioid intracellular receptor 1 |
Synonyms: | Aging-associated gene 8 protein | OPRS1 | SGMR1_HUMAN | SIG-1R | SIGMAR1 | SR-BP | SR31747-binding protein | SRBP | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1 |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 25124.85 |
Organism: | Homo sapiens (Human) |
Description: | Q99720 |
Residue: | 223 |
Sequence: | MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
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BDBM50006983 |
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n/a |
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Name | BDBM50006983 |
Synonyms: | CHEMBL55873 | N-Adamantan-1-yl-N'-(4-methoxy-2-methyl-phenyl)-guanidine |
Type | Small organic molecule |
Emp. Form. | C19H27N3O |
Mol. Mass. | 313.4372 |
SMILES | COc1ccc(N=C(N)NC23CC4CC(CC(C4)C2)C3)c(C)c1 |w:6.5,TLB:17:16:19:12.11.13,17:12:19:16.18.15,13:14:18:12.11.17,THB:13:12:18:14.19.15| |
Structure |
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