| Reaction Details |
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 | Report a problem with these data |
| Target | Mu-type opioid receptor |
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| Ligand | BDBM50007002 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_146418 (CHEMBL757170) |
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| Ki | 21±n/a nM |
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| Citation |  Freeman, JP; Michalson, ET; D'Andrea, SV; Baczynskyj, L; Von Voigtlander, PF; Lahti, RA; Smith, MW; Lawson, CF; Scahill, TA; Mizsak, SA Naphtho and benzo analogues of the kappa opioid agonist trans-(+/-)-3,4-dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl] benzeneacetamide. J Med Chem34:1891-6 (1991) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Mu-type opioid receptor |
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| Name: | Mu-type opioid receptor |
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| Synonyms: | M-OR-1 | MOR-1 | Mor | OPIATE Mu | OPRM_MOUSE | Opioid receptors; mu and delta | Oprm | Oprm1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 44431.62 |
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| Organism: | MOUSE |
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| Description: | OPIATE Mu OPRM1 MOUSE::P42866 |
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| Residue: | 398 |
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| Sequence: | MDSSAGPGNISDCSDPLAPASCSPAPGSWLNLSHVDGNQSDPCGPNRTGLGGSHSLCPQT
GSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATST
LPFQSVNYLMGTWPFGNILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRT
PRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFA
FIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYV
IIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQ
QNSARIRQNTREHPSTANTVDRTNHQLENLEAETAPLP
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| BDBM50007002 |
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| n/a |
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| Name | BDBM50007002 |
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| Synonyms: | 3,4-Dichloro-N-(3-dimethylamino-1,2,3,4-tetrahydro-naphthalen-2-yl)-N-methyl-benzamide | CHEMBL296184 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H22Cl2N2O |
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| Mol. Mass. | 377.307 |
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| SMILES | CN(C)[C@@H]1Cc2ccccc2C[C@H]1N(C)C(=O)c1ccc(Cl)c(Cl)c1 |
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| Structure | 
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