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TargetDelta-type opioid receptor
LigandBDBM50007166
Substrate/Competitorn/a
Meas. Tech.ChEBML_146436
Ki 362±n/a nM
Citation Vecchietti, VClarke, GDColle, RGiardina, GPetrone, GSbacchi, M (1S)-1-(aminomethyl)-2-(arylacetyl)-1,2,3,4-tetrahydroisoquinoline and heterocycle-condensed tetrahydropyridine derivatives: members of a novel class of very potent kappa opioid analgesics. J Med Chem34:2624-33 (1991) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Delta-type opioid receptor
Name:Delta-type opioid receptor
Synonyms:D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:40382.98
Organism:Homo sapiens (Human)
Description:Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
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  Blast E-value cutoff:
BDBM50007166
n/a
NameBDBM50007166
Synonyms:2-(3,4-Dichloro-phenyl)-1-(7-pyrrolidin-1-ylmethyl-4,7-dihydro-5H-thieno[2,3-c]pyridin-6-yl)-ethanone;HCl | CHEMBL88168
TypeSmall organic molecule
Emp. Form.C20H22Cl2N2OS
Mol. Mass.409.372
SMILESClc1ccc(CC(=O)N2CCc3ccsc3C2CN2CCCC2)cc1Cl
Structure
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