| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase-related protein 11 |
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| Ligand | BDBM50253871 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_1685888 |
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| Ki | 4.1±n/a nM |
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| Citation |  Karal?, N; Akdemir, A; Gökta?, F; Eraslan Elma, P; Angeli, A; K?z?l?rmak, M; Supuran, CT Novel sulfonamide-containing 2-indolinones that selectively inhibit tumor-associated alpha carbonic anhydrases. Bioorg Med Chem25:3714-3718 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase-related protein 11 |
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| Name: | Carbonic anhydrase-related protein 11 |
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| Synonyms: | CA-RP II | CA-RP XI | CA-XI | CA11 | CAH11_HUMAN | CARP XI | CARP-2 | CARP2 | CARP2 | Carbonic anhydrase-related protein 11 | Carbonic anhydrase-related protein 2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 36252.43 |
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| Organism: | Homo sapiens |
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| Description: | ChEMBL_12954 |
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| Residue: | 328 |
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| Sequence: | MGAAARLSAPRALVLWAALGAAAHIGPAPDPEDWWSYKDNLQGNFVPGPPFWGLVNAAWS
LCAVGKRQSPVDVELKRVLYDPFLPPLRLSTGGEKLRGTLYNTGRHVSFLPAPRPVVNVS
GGPLLYSHRLSELRLLFGARDGAGSEHQINHQGFSAEVQLIHFNQELYGNFSAASRGPNG
LAILSLFVNVASTSNPFLSRLLNRDTITRISYKNDAYFLQDLSLELLFPESFGFITYQGS
LSTPPCSETVTWILIDRALNITSLQMHSLRLLSQNPPSQIFQSLSGNSRPLQPLAHRALR
GNRDPRHPERRCRGPNYRLHVDGVPHGR
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| BDBM50253871 |
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| n/a |
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| Name | BDBM50253871 |
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| Synonyms: | CHEMBL4097126 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H12N6O5S2 |
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| Mol. Mass. | 420.423 |
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| SMILES | NS(=O)(=O)c1ccc(NC(=S)N\N=C2/C(=O)Nc3ccc(cc23)[N+]([O-])=O)cc1 |
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| Structure | 
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