| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-1 adrenergic receptor |
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| Ligand | BDBM50007476 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_37546 |
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| Ki | 120±n/a nM |
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| Citation |  Adejare, A; Nie, JY; Hebel, D; Brackett, LE; Choi, O; Gusovsky, F; Padgett, WL; Daly, JW; Creveling, CR; Kirk, KL Effect of fluorine substitution on the adrenergic properties of 3-(tert-butylamino)-1-(3,4-dihydroxyphenoxy)-2-propanol. J Med Chem34:1063-8 (1991) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-1 adrenergic receptor |
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| Name: | Beta-1 adrenergic receptor |
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| Synonyms: | ADRB1R, B1AR | ADRB1_RAT | Adrb1 | Adrb1r | Adrenergic receptor beta | Beta-1 adrenoceptor | Beta-1 adrenoreceptor | adrenergic Beta1 | adrenergic Beta1,2 |
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| Type: | Protein |
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| Mol. Mass.: | 50486.84 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | P18090 |
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| Residue: | 466 |
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| Sequence: | MGAGALALGASEPCNLSSAAPLPDGAATAARLLVLASPPASLLPPASEGSAPLSQQWTAG
MGLLLALIVLLIVVGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVV
WGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITLPFRYQSLLTRARARALVC
TVWAISALVSFLPILMHWWRAESDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIM
AFVYLRVFREAQKQVKKIDSCERRFLTGPPRPPSPAPSPSPGPPRPADSLANGRSSKRRP
SRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRDLVPDRLFVFFNWLGYANSA
FNPIIYCRSPDFRKAFQRLLCCARRAACRRRAAHGDRPRASGCLARAGPPPSPGAPSDDD
DDDAGATPPARLLEPWAGCNGGTTTVDSDSSLDEPGRQGFSSESKV
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|
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| BDBM50007476 |
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| n/a |
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| Name | BDBM50007476 |
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| Synonyms: | 4-(3-tert-Butylamino-2-hydroxy-propoxy)-benzene-1,2-diol | CHEMBL266619 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H21NO4 |
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| Mol. Mass. | 255.3101 |
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| SMILES | CC(C)(C)NCC(O)COc1ccc(O)c(O)c1 |
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| Structure | 
|
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