| Reaction Details |
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 | Report a problem with these data |
| Target | Kappa-type opioid receptor |
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| Ligand | BDBM50254705 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1686384 (CHEMBL4036863) |
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| Ki | 85±n/a nM |
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| Citation |  Bohn, LM; Aubé, J Seeking (and Finding) Biased Ligands of the Kappa Opioid Receptor. ACS Med Chem Lett8:694-700 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Kappa-type opioid receptor |
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| Name: | Kappa-type opioid receptor |
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| Synonyms: | K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 42648.76 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P41145 |
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| Residue: | 380 |
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| Sequence: | MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRV
RNTVQDPAYLRDIDGMNKPV
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| BDBM50254705 |
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| n/a |
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| Name | BDBM50254705 |
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| Synonyms: | CHEMBL4068633 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H24F4N2O2 |
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| Mol. Mass. | 460.4639 |
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| SMILES | [H][C@]12CCN(Cc3ccccc3F)C(=O)[C@@]1([H])[C@H](CC=C2)C(=O)Nc1ccc(C)c(c1)C(F)(F)F |r,c:21| |
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| Structure | 
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