| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosylhomocysteinase |
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| Ligand | BDBM50008288 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_196872 |
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| IC50 | 721±n/a nM |
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| Citation |  Shuto, S; Obara, T; Toriya, M; Hosoya, M; Snoeck, R; Andrei, G; Balzarini, J; De Clercq, E New neplanocin analogues. 1. Synthesis of 6'-modified neplanocin A derivatives as broad-spectrum antiviral agents. J Med Chem35:324-31 (1992) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosylhomocysteinase |
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| Name: | Adenosylhomocysteinase |
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| Synonyms: | AHCY | Adenosylhomocysteinase | SAHH | SAHH_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 47714.06 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1507791 |
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| Residue: | 432 |
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| Sequence: | MSDKLPYKVADIGLAAWGRKALDIAENEMPGLMRMRERYSASKPLKGARIAGCLHMTVET
AVLIETLVTLGAEVQWSSCNIFSTQDHAAAAIAKAGIPVYAWKGETDEEYLWCIEQTLYF
KDGPLNMILDDGGDLTNLIHTKYPQLLPGIRGISEETTTGVHNLYKMMANGILKVPAINV
NDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVI
ITEIDPINALQAAMEGYEVTTMDEACQEGNIFVTTTGCIDIILGRHFEQMKDDAIVCNIG
HFDVEIDVKWLNENAVEKVNIKPQVDRYRLKNGRRIILLAEGRLVNLGCAMGHPSFVMSN
SFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMS
CDGPFKPDHYRY
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| BDBM50008288 |
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| n/a |
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| Name | BDBM50008288 |
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| Synonyms: | (1S,2R,5R)-5-(6-Amino-purin-9-yl)-3-((R)-1-hydroxy-ethyl)-cyclopent-3-ene-1,2-diol | 5-(6-Amino-purin-9-yl)-3-(1-hydroxy-ethyl)-cyclopent-3-ene-1,2-diol | CHEMBL327105 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H15N5O3 |
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| Mol. Mass. | 277.2792 |
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| SMILES | C[C@@H](O)C1=C[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12 |t:3| |
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| Structure | 
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