| Reaction Details |
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 | Report a problem with these data |
| Target | D(3) dopamine receptor |
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| Ligand | BDBM50325746 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_1691277 |
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| Ki | 1.000000±n/a nM |
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| Citation |  Levoin, N; Labeeuw, O; Billot, X; Calmels, T; Danvy, D; Krief, S; Berrebi-Bertrand, I; Lecomte, JM; Schwartz, JC; Capet, M Discovery of nanomolar ligands with novel scaffolds for the histamine H4 receptor by virtual screening. Eur J Med Chem125:565-572 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(3) dopamine receptor |
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| Name: | D(3) dopamine receptor |
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| Synonyms: | DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3 |
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| Type: | n/a |
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| Mol. Mass.: | 44243.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 400 |
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| Sequence: | MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
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| BDBM50325746 |
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| n/a |
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| Name | BDBM50325746 |
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| Synonyms: | CHEMBL1223748 | N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)isoquinolin-1-amine |
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| Type | Small organic molecule |
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| Emp. Form. | C24H30N4O |
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| Mol. Mass. | 390.5212 |
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| SMILES | COc1ccccc1N1CCN(CCCCNc2nccc3ccccc23)CC1 |
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| Structure | 
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