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TargetDual specificity protein kinase CLK2
LigandBDBM50259467
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1691311
IC50 47±n/a nM
Citation Bendjeddou LZLoaëc NVilliers BPrina ESpäth GFGalons HMeijer LOumata N Exploration of the imidazo[1,2-b]pyridazine scaffold as a protein kinase inhibitor. Eur J Med Chem 125:696-709 (2017) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Dual specificity protein kinase CLK2
Name:Dual specificity protein kinase CLK2
Synonyms:CDC-like kinase 2
Type:PROTEIN
Mol. Mass.:60021.57
Organism:Mus musculus
Description:ChEMBL_1502246
Residue:499
Sequence:
MPHPRRYHSSERGSRGSYHEHYQSRKHKRRRSRSWSSSSDRTRRRRREDSYHVRSRSSYD
DHSSDRRLYDRRYCGSYRRNDYSRDRGEAYYDTDFRQSYEYHRENSSYRSQRSSRRKHRR
RRRRSRTFSRSSSHSSRRAKSVEDDAEGHLIYHVGDWLQERYEIVSTLGEGTFGRVVQCV
DHRRGGTQVALKIIKNVEKYKEAARLEINVLEKINEKDPDNKNLCVQMFDWFDYHGHMCI
SFELLGLSTFDFLKDNNYLPYPIHQVRHMAFQLCQAVKFLHDNKLTHTDLKPENILFVNS
DYELTYNLEKKRDERSVKSTAVRVVDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQP
CDVWSIGCIIFEYYVGFTLFQTHDNREHLAMMERILGPVPSRMIRKTRKQKYFYRGRLDW
DENTSAGRYVRENCKPLRRYLTSEAEDHHQLFDLIENMLEYEPAKRLTLGEALQHPFFAC
LRTEPPNTKLWDSSRDISR
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  Blast E-value cutoff:
BDBM50259467
n/a
NameBDBM50259467
Synonyms:CHEMBL4070189
TypeSmall organic molecule
Emp. Form.C17H20N4O3S
Mol. Mass.360.431
SMILESCC[C@@H](CO)Nc1ccc2ncc(-c3cccc(c3)S(C)(=O)=O)n2n1 |r|
Structure
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