| Reaction Details |
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 | Report a problem with these data |
| Target | G-protein coupled receptor 35 |
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| Ligand | BDBM50131066 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1691965 (CHEMBL4042614) |
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| IC50 | 100000±n/a nM |
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| Citation |  Wei, L; Wang, J; Zhang, X; Wang, P; Zhao, Y; Li, J; Hou, T; Qu, L; Shi, L; Liang, X; Fang, Y Discovery of 2H-Chromen-2-one Derivatives as G Protein-Coupled Receptor-35 Agonists. J Med Chem60:362-372 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| G-protein coupled receptor 35 |
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| Name: | G-protein coupled receptor 35 |
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| Synonyms: | G protein-coupled receptor 35 | GPR35 | GPR35_HUMAN |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 34085.57 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_33695097 |
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| Residue: | 309 |
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| Sequence: | MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMT
NLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRH
PLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGF
YLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVR
LAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKS
QDSLCVTLA
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| BDBM50131066 |
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| n/a |
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| Name | BDBM50131066 |
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| Synonyms: | 2-Oxo-2H-chromene-3-carboxylic acid | CHEMBL83294 |
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| Type | Small organic molecule |
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| Emp. Form. | C10H6O4 |
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| Mol. Mass. | 190.1522 |
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| SMILES | OC(=O)c1cc2ccccc2oc1=O |
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| Structure | 
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