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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | 5-hydroxytryptamine receptor 3A | ||
| Ligand | BDBM50259917 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEBML_1691999 | ||
| IC50 | 32000±n/a nM | ||
| Citation |  Hill, MD; Fang, H; Digavalli, SV; Healy, FL; Gallagher, L; Post-Munson, D; Chen, P; Natale, J; Benitex, Y; Morgan, D; Lodge, N; Bristow, L; Macor, JE; Olson, RE Development of spiroguanidine-derived?7 neuronal nicotinic receptor partial agonists. Bioorg Med Chem Lett27:578-581 (2017) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| 5-hydroxytryptamine receptor 3A | |||
| Name: | 5-hydroxytryptamine receptor 3A | ||
| Synonyms: | 5-HT-3 | 5-HT3 | 5-HT3A | 5-HT3R | 5-hydroxytryptamine receptor 3 (5-HT3) | 5-hydroxytryptamine receptor 3A (5-HT3a) | 5-hydroxytryptamine receptor 3A (5HT3A) | 5HT3A_HUMAN | 5HT3R | HTR3 | HTR3A | Serotonin 3 (5-HT3) receptor | Serotonin 3 receptor (5HT3) | Serotonin receptor 3A | Serotonin-gated ion channel receptor | Serotonin-gated ion channel receptor 3 | ||
| Type: | Protein | ||
| Mol. Mass.: | 55283.27 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P46098 | ||
| Residue: | 478 | ||
| Sequence: |
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| BDBM50259917 | |||
| n/a | |||
| Name | BDBM50259917 | ||
| Synonyms: | CHEMBL4088682 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C17H21N5OS | ||
| Mol. Mass. | 343.447 | ||
| SMILES | COc1ccc2nc(NC3=NCC4(CN5CCC4CC5)N3)sc2c1 |t:9,THB:20:12:15.16:18.19,(52.97,-17.62,;52.98,-19.16,;51.65,-19.94,;51.65,-21.48,;50.32,-22.25,;48.99,-21.48,;47.52,-21.96,;46.61,-20.72,;45.07,-20.72,;44.3,-22.05,;44.92,-23.46,;43.78,-24.49,;42.44,-23.72,;42.23,-25.11,;40.31,-24.3,;38.91,-25.23,;39.26,-23.83,;40.96,-23.08,;40.89,-21.44,;40.31,-22.83,;42.77,-22.21,;47.52,-19.46,;48.99,-19.94,;50.32,-19.17,)| | ||
| Structure | 
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