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TargetThromboxane A2 receptor
LigandBDBM50010073
Substrate/Competitorn/a
Meas. Tech.ChEBML_209599
Kd 1±n/a nM
Citation Misra, RNBrown, BRHan, WCHarris, DNHedberg, AWebb, MLHall, SE Interphenylene 7-oxabicyclo[2.2.1]heptane thromboxane A2 antagonists. Semicarbazone omega-chains. J Med Chem34:2882-91 (1991) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Thromboxane A2 receptor
Name:Thromboxane A2 receptor
Synonyms:Prostanoid TP receptor | TA2R_HUMAN | TBXA2R | TXA2-R | Thromboxane | Thromboxane A2 receptor | Thromboxane Beta
Type:Enyzme
Mol. Mass.:37445.28
Organism:Homo sapiens (Human)
Description:P21731
Residue:343
Sequence:
MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTR
SSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPL
LLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPG
SWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSE
VEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWN
QILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
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  Blast E-value cutoff:
BDBM50010073
n/a
NameBDBM50010073
Synonyms:3-(2-{3-[(E)-Phenylcarbamoylmethylimino-amino]-7-oxa-bicyclo[2.2.1]hept-2-ylmethyl}-phenyl)-propionic acid | 3-[2-(5-oxabicyclo[2.2.1],3-formaldehyde (anilinocarbonyl)hydrazonehept-2-ylmethyl)phenyl]propanoic acid | CHEMBL95872
TypeSmall organic molecule
Emp. Form.C24H27N3O4
Mol. Mass.421.4889
SMILESOC(=O)CCc1ccccc1CC1C2CCC(O2)C1C=NNC(=O)Nc1ccccc1 |w:20.23,THB:19:18:17:15.14|
Structure
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