| Reaction Details |
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 | Report a problem with these data |
| Target | Melatonin receptor type 1B |
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| Ligand | BDBM50263700 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_1698236 |
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| Ki | 0.220000±n/a nM |
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| Citation |  Rivara, S; Scalvini, L; Lodola, A; Mor, M; Caignard, DH; Delagrange, P; Collina, S; Lucini, V; Scaglione, F; Furiassi, L; Mari, M; Lucarini, S; Bedini, A; Spadoni, G Tetrahydroquinoline Ring as a Versatile Bioisostere of Tetralin for Melatonin Receptor Ligands. J Med Chem61:3726-3737 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Melatonin receptor type 1B |
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| Name: | Melatonin receptor type 1B |
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| Synonyms: | MTNR1B | MTR1B_HUMAN | Mel-1B-R | Mel1b melatonin receptor | Melatonin 1B | Melatonin receptor | Melatonin receptor type 1B | Melatonin receptor type 2 (MT2) |
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| Type: | Enzyme |
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| Mol. Mass.: | 40203.54 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P49286 |
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| Residue: | 362 |
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| Sequence: | MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLL
VILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVM
GLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGS
LEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRL
CLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFN
SCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQAD
AL
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| BDBM50263700 |
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| n/a |
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| Name | BDBM50263700 |
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| Synonyms: | CHEMBL4083618 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H23NO |
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| Mol. Mass. | 293.4027 |
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| SMILES | CCC(=O)NC[C@@H]1CCc2ccccc2[C@@H]1c1ccccc1 |r| |
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| Structure | 
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