| Reaction Details |
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 | Report a problem with these data |
| Target | B-cell lymphoma 6 protein |
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| Ligand | BDBM50266780 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1701343 (CHEMBL4052325) |
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| IC50 | 480±n/a nM |
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| Citation |  Kamada, Y; Sakai, N; Sogabe, S; Ida, K; Oki, H; Sakamoto, K; Lane, W; Snell, G; Iida, M; Imaeda, Y; Sakamoto, J; Matsui, J Discovery of a B-Cell Lymphoma 6 Protein-Protein Interaction Inhibitor by a Biophysics-Driven Fragment-Based Approach. J Med Chem60:4358-4368 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| B-cell lymphoma 6 protein |
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| Name: | B-cell lymphoma 6 protein |
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| Synonyms: | B-cell lymphoma 5 protein | B-cell lymphoma 6 protein | BCL-5 | BCL-6 | BCL5 | BCL6 | BCL6_HUMAN | BCoR-BCL6 | LAZ3 | Protein LAZ-3 | ZBTB27 | ZNF51 | Zinc finger and BTB domain-containing protein 27 | Zinc finger protein 51 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 78866.89 |
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| Organism: | Homo sapiens |
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| Description: | ChEMBL_117695 |
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| Residue: | 706 |
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| Sequence: | MASPADSCIQFTRHASDVLLNLNRLRSRDILTDVVIVVSREQFRAHKTVLMACSGLFYSI
FTDQLKCNLSVINLDPEINPEGFCILLDFMYTSRLNLREGNIMAVMATAMYLQMEHVVDT
CRKFIKASEAEMVSAIKPPREEFLNSRMLMPQDIMAYRGREVVENNLPLRSAPGCESRAF
APSLYSGLSTPPASYSMYSHLPVSSLLFSDEEFRDVRMPVANPFPKERALPCDSARPVPG
EYSRPTLEVSPNVCHSNIYSPKETIPEEARSDMHYSVAEGLKPAAPSARNAPYFPCDKAS
KEEERPSSEDEIALHFEPPNAPLNRKGLVSPQSPQKSDCQPNSPTESCSSKNACILQASG
SPPAKSPTDPKACNWKKYKFIVLNSLNQNAKPEGPEQAELGRLSPRAYTAPPACQPPMEP
ENLDLQSPTKLSASGEDSTIPQASRLNNIVNRSMTGSPRSSSESHSPLYMHPPKCTSCGS
QSPQHAEMCLHTAGPTFPEEMGETQSEYSDSSCENGAFFCNECDCRFSEEASLKRHTLQT
HSDKPYKCDRCQASFRYKGNLASHKTVHTGEKPYRCNICGAQFNRPANLKTHTRIHSGEK
PYKCETCGARFVQVAHLRAHVLIHTGEKPYPCEICGTRFRHLQTLKSHLRIHTGEKPYHC
EKCNLHFRHKSQLRLHLRQKHGAITNTKVQYRVSATDLPPELPKAC
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| BDBM50266780 |
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| n/a |
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| Name | BDBM50266780 |
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| Synonyms: | CHEMBL4077392 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H15ClN6O |
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| Mol. Mass. | 366.804 |
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| SMILES | Clc1cnc(NCc2cccnc2)nc1Nc1ccc2NC(=O)Cc2c1 |
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| Structure | 
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