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TargetHuman immunodeficiency virus type 1 protease
LigandBDBM50010495
Substrate/Competitorn/a
Meas. Tech.ChEMBL_158642
Ki 0.600000±n/a nM
Citation Rich DHSun CQVara Prasad JVPathiasseril AToth MVMarshall GRClare MMueller RAHouseman K Effect of hydroxyl group configuration in hydroxyethylamine dipeptide isosteres on HIV protease inhibition. Evidence for multiple binding modes. J Med Chem 34:1222-5 (1991) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Human immunodeficiency virus type 1 protease
Name:Human immunodeficiency virus type 1 protease
Synonyms:Pol polyprotein
Type:Enzyme Subunit
Mol. Mass.:10781.16
Organism:Human immunodeficiency virus type 1
Description:n/a
Residue:99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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  Blast E-value cutoff:
BDBM50010495
n/a
NameBDBM50010495
Synonyms:Acetyl-Ser-Leu-Asn-Phe-[CH(OH)CH2N]Pro-Ile-Val-OMe | CHEMBL432614
TypeSmall organic molecule
Emp. Form.C42H68N8O11
Mol. Mass.861.0363
SMILESCC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1CC(O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](C(C)C)C(=O)OC
Structure
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