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TargetPlatelet activating factor receptor
LigandBDBM50013931
Substrate/Competitorn/a
Meas. Tech.ChEBML_154992
IC50 55±n/a nM
Citation Guthrie RWKaplan GLMennona FATilley JWKierstead RWO'Donnell MCrowley HYaremko BWelton AF Propenyl carboxamide derivatives as antagonists of platelet activating factor. J Med Chem 33:2856-64 (1990) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Platelet activating factor receptor
Name:Platelet activating factor receptor
Synonyms:PAF Platelet activating factor | PAF-R | Platelet-activating factor receptor
Type:Enzyme Catalytic Domain
Mol. Mass.:39219.60
Organism:Homo sapiens (Human)
Description:PAF Platelet activating factor PTAFR HUMAN::P25105
Residue:342
Sequence:
MEPHDSSHMDSEFRYTLFPIVYSIIFVLGVIANGYVLWVFARLYPCKKFNEIKIFMVNLT
MADMLFLITLPLWIVYYQNQGNWILPKFLCNVAGCLFFINTYCSVAFLGVITYNRFQAVT
RPIKTAQANTRKRGISLSLVIWVAIVGAASYFLILDSTNTVPDSAGSGNVTRCFEHYEKG
SVPVLIIHIFIVFSFFLVFLIILFCNLVIIRTLLMQPVQQQRNAEVKRRALWMVCTVLAV
FIICFVPHHVVQLPWTLAELGFQDSKFHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKF
RKHLTEKFYSMRSSRKCSRATTDTVTEVVVPFNQIPGNSLKN
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50013931
n/a
NameBDBM50013931
Synonyms:3-[6-Methoxy-1-(4-methoxy-phenyl)-naphthalen-2-yl]-N-(1-methyl-4-pyridin-3-yl-butyl)-acrylamide | CHEMBL319568
TypeSmall organic molecule
Emp. Form.C31H32N2O3
Mol. Mass.480.5974
SMILESCOc1ccc(cc1)-c1c(\C=C\C(=O)N[C@@H](C)CCCc2cccnc2)ccc2cc(OC)ccc12
Structure
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