| Reaction Details |
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 | Report a problem with these data |
| Target | Platelet-activating factor receptor |
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| Ligand | BDBM50013931 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_154992 |
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| IC50 | 55±n/a nM |
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| Citation |  Guthrie, RW; Kaplan, GL; Mennona, FA; Tilley, JW; Kierstead, RW; O'Donnell, M; Crowley, H; Yaremko, B; Welton, AF Propenyl carboxamide derivatives as antagonists of platelet activating factor. J Med Chem33:2856-64 (1990) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Platelet-activating factor receptor |
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| Name: | Platelet-activating factor receptor |
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| Synonyms: | PAF Platelet activating factor | PAF-R | PAFR | PTAFR | PTAFR_HUMAN | Platelet activating factor receptor | Platelet-activating factor receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 39219.60 |
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| Organism: | Homo sapiens (Human) |
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| Description: | PAF Platelet activating factor PTAFR HUMAN::P25105 |
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| Residue: | 342 |
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| Sequence: | MEPHDSSHMDSEFRYTLFPIVYSIIFVLGVIANGYVLWVFARLYPCKKFNEIKIFMVNLT
MADMLFLITLPLWIVYYQNQGNWILPKFLCNVAGCLFFINTYCSVAFLGVITYNRFQAVT
RPIKTAQANTRKRGISLSLVIWVAIVGAASYFLILDSTNTVPDSAGSGNVTRCFEHYEKG
SVPVLIIHIFIVFSFFLVFLIILFCNLVIIRTLLMQPVQQQRNAEVKRRALWMVCTVLAV
FIICFVPHHVVQLPWTLAELGFQDSKFHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKF
RKHLTEKFYSMRSSRKCSRATTDTVTEVVVPFNQIPGNSLKN
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| BDBM50013931 |
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| n/a |
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| Name | BDBM50013931 |
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| Synonyms: | 3-[6-Methoxy-1-(4-methoxy-phenyl)-naphthalen-2-yl]-N-(1-methyl-4-pyridin-3-yl-butyl)-acrylamide | CHEMBL319568 |
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| Type | Small organic molecule |
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| Emp. Form. | C31H32N2O3 |
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| Mol. Mass. | 480.5974 |
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| SMILES | COc1ccc(cc1)-c1c(\C=C\C(=O)N[C@@H](C)CCCc2cccnc2)ccc2cc(OC)ccc12 |
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| Structure | 
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