| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Renin |
|---|
| Ligand | BDBM50014101 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_196424 |
|---|
| IC50 | 1.1±n/a nM |
|---|
| Citation |  Bundy, GL; Pals, DT; Lawson, JA; Couch, SJ; Lipton, MF; Mauragis, MA Potent renin inhibitory peptides containing hydrophilic end groups. J Med Chem33:2276-83 (1990) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Renin |
|---|
| Name: | Renin |
|---|
| Synonyms: | RENI_RAT | Ren | Ren1 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 44272.67 |
|---|
| Organism: | Rattus norvegicus |
|---|
| Description: | ChEMBL_222765 |
|---|
| Residue: | 402 |
|---|
| Sequence: | MGGRRMPLWALLLLWTSCSFSLPTDTASFGRILLKKMPSVREILEERGVDMTRISAEWGE
FIKKSSFTNVTSPVVLTNYLDTQYYGEIGIGTPSQTFKVIFDTGSANLWVPSTKCGPLYT
ACEIHNLYDSSESSSYMENGTEFTIHYGSGKVKGFLSQDVVTVGGIIVTQTFGEVTELPL
IPFMLAKFDGVLGMGFPAQAVDGVIPVFDHILSQRVLKEEVFSVYYSRESHLLGGEVVLG
GSDPQHYQGNFHYVSISKAGSWQITMKGVSVGPATLLCEEGCMAVVDTGTSYISGPTSSL
QLIMQALGVKEKRANNYVVNCSQVPTLPDISFYLGGRTYTLSNMDYVQKNPFRNDDLCIL
ALQGLDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR
|
|
|
|---|
| BDBM50014101 |
|---|
| n/a |
|---|
| Name | BDBM50014101 |
|---|
| Synonyms: | CHEMBL265833 | N-[4,5-Dihydro-4,4-bis(hydroxymethyl)-2-oxazolyl]-Pro-Phe-N(Me) His-Leu[CHOHCH2]val-Ile-AmpO |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C50H73N9O10 |
|---|
| Mol. Mass. | 960.1689 |
|---|
| SMILES | CC[C@H](C)[C@H](NC(=O)[C@H](C[C@H](O)[C@H](CC(C)C)NC(=O)[C@H](Cc1cnc[nH]1)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C1=NC(CO)(CO)CO1)C(C)C)C(=O)OCc1ccccn1 |t:50| |
|---|
| Structure | 
|
|---|
Search and Browse
