| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Alpha-1B adrenergic receptor |
|---|
| Ligand | BDBM50274053 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1713734 (CHEMBL4123783) |
|---|
| Ki | 0.128825±n/a nM |
|---|
| Citation |  Sagratini, G; Buccioni, M; Marucci, G; Poggesi, E; Skorski, M; Costanzi, S; Giardinà, D Chiral analogues of (+)-cyclazosin as potent? Bioorg Med Chem26:3502-3513 (2018) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Alpha-1B adrenergic receptor |
|---|
| Name: | Alpha-1B adrenergic receptor |
|---|
| Synonyms: | ADA1B_HUMAN | ADRA1B | Adrenergic alpha1B | Adrenergic receptor | Adrenergic receptor alpha | Alpha 1B-adrenoceptor | Alpha 1B-adrenoreceptor | Alpha-1B adrenergic receptor |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 56862.13 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P35368 |
|---|
| Residue: | 520 |
|---|
| Sequence: | MNPDLDTGHNTSAPAHWGELKNANFTGPNQTSSNSTLPQLDITRAISVGLVLGAFILFAI
VGNILVILSVACNRHLRTPTNYFIVNLAMADLLLSFTVLPFSAALEVLGYWVLGRIFCDI
WAAVDVLCCTASILSLCAISIDRYIGVRYSLQYPTLVTRRKAILALLSVWVLSTVISIGP
LLGWKEPAPNDDKECGVTEEPFYALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLEAG
VMKEMSNSKELTLRIHSKNFHEDTLSSTKAKGHNPRSSIAVKLFKFSREKKAAKTLGIVV
GMFILCWLPFFIALPLGSLFSTLKPPDAVFKVVFWLGYFNSCLNPIIYPCSSKEFKRAFV
RILGCQCRGRGRRRRRRRRRLGGCAYTYRPWTRGGSLERSQSRKDSLDDSGSCLSGSQRT
LPSASPSPGYLGRGAPPPVELCAFPEWKAPGALLSLPAPEPPGRRGRHDSGPLFTFKLLT
EPESPGTDGGASNGGCEAAADVANGQPGFKSNMPLAPGQF
|
|
|
|---|
| BDBM50274053 |
|---|
| n/a |
|---|
| Name | BDBM50274053 |
|---|
| Synonyms: | CHEMBL4126860 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C29H39N5O4 |
|---|
| Mol. Mass. | 521.6511 |
|---|
| SMILES | [H][C@@]12CCCC[C@]1([H])N(CCN2C(=O)c1ccco1)c1nc(N(CCC)CCC)c2cc(OC)c(OC)cc2n1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
