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TargetChymotrypsinogen B
LigandBDBM50014731
Substrate/Competitorn/a
Meas. Tech.ChEMBL_216618 (CHEMBL819190)
Ki 79±n/a nM
Citation Peet, NPBurkhart, JPAngelastro, MRGiroux, ELMehdi, SBey, PKolb, MNeises, BSchirlin, D Synthesis of peptidyl fluoromethyl ketones and peptidyl alpha-keto esters as inhibitors of porcine pancreatic elastase, human neutrophil elastase, and rat and human neutrophil cathepsin G. J Med Chem33:394-407 (1990) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Chymotrypsinogen B
Name:Chymotrypsinogen B
Synonyms:Beta-chymotrypsin | CTRB | CTRB1 | CTRB1_HUMAN | Chymotrypsin B chain A | Chymotrypsin B chain B | Chymotrypsin B chain C | Chymotrypsinogen B | Synonyms=CTRB
Type:PROTEIN
Mol. Mass.:27713.98
Organism:Homo sapiens (Human)
Description:ChEMBL_10909
Residue:263
Sequence:
MASLWLLSCFSLVGAAFGCGVPAIHPVLSGLSRIVNGEDAVPGSWPWQVSLQDKTGFHFC
GGSLISEDWVVTAAHCGVRTSDVVVAGEFDQGSDEENIQVLKIAKVFKNPKFSILTVNND
ITLLKLATPARFSQTVSAVCLPSADDDFPAGTLCATTGWGKTKYNANKTPDKLQQAALPL
LSNAECKKSWGRRITDVMICAGASGVSSCMGDSGGPLVCQKDGAWTLVGIVSWGSDTCST
SSPGVYARVTKLIPWVQKILAAN
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  Blast E-value cutoff:
BDBM50014731
n/a
NameBDBM50014731
Synonyms:3-[(1-{2-[2-(3-Methoxycarbonyl-propionylamino)-propionylamino]-propionyl}-pyrrolidine-2-carbonyl)-amino]-2-oxo-4-phenyl-butyric acid methyl ester | CHEMBL130006
TypeSmall organic molecule
Emp. Form.C27H36N4O9
Mol. Mass.560.5961
SMILESCOC(=O)CCC(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)C(=O)OC
Structure
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