| Reaction Details |
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 | Report a problem with these data |
| Target | Cathepsin G |
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| Ligand | BDBM50014746 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_45359 |
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| Ki | 1100±n/a nM |
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| Citation |  Peet, NP; Burkhart, JP; Angelastro, MR; Giroux, EL; Mehdi, S; Bey, P; Kolb, M; Neises, B; Schirlin, D Synthesis of peptidyl fluoromethyl ketones and peptidyl alpha-keto esters as inhibitors of porcine pancreatic elastase, human neutrophil elastase, and rat and human neutrophil cathepsin G. J Med Chem33:394-407 (1990) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Cathepsin G |
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| Name: | Cathepsin G |
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| Synonyms: | CATG_HUMAN | CG | CTSG |
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| Type: | PROTEIN |
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| Mol. Mass.: | 28860.08 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1469016 |
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| Residue: | 255 |
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| Sequence: | MQPLLLLLAFLLPTGAEAGEIIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVL
TAAHCWGSNINVTLGAHNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRR
NRNVNPVALPRAQEGLRPGTLCTVAGWGRVSMRRGTDTLREVQLRVQRDRQCLRIFGSYD
PRRQICVGDRRERKAAFKGDSGGPLLCNNVAHGIVSYGKSSGVPPEVFTRVSSFLPWIRT
TMRSFKLLDQMETPL
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| BDBM50014746 |
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| n/a |
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| Name | BDBM50014746 |
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| Synonyms: | 3-({1-[2-(3-Methoxycarbonyl-propionylamino)-3-methyl-butyryl]-pyrrolidine-2-carbonyl}-amino)-2-oxo-4-phenyl-butyric acid methyl ester | CHEMBL130656 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H35N3O8 |
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| Mol. Mass. | 517.5714 |
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| SMILES | COC(=O)CCC(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)C(=O)OC |
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| Structure | 
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