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TargetElastase 1
LigandBDBM50014733
Substrate/Competitorn/a
Meas. Tech.ChEBML_63628
Ki 4300±n/a nM
Citation Peet NPBurkhart JPAngelastro MRGiroux ELMehdi SBey PKolb MNeises BSchirlin D Synthesis of peptidyl fluoromethyl ketones and peptidyl alpha-keto esters as inhibitors of porcine pancreatic elastase, human neutrophil elastase, and rat and human neutrophil cathepsin G. J Med Chem 33:394-407 (1990) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Elastase 1
Name:Elastase 1
Synonyms:Elastase-1
Type:PROTEIN
Mol. Mass.:27805.35
Organism:Homo sapiens (Human)
Description:ChEMBL_63626
Residue:258
Sequence:
MLVLYGHSTQDLPETNARVVGGTEAGRNSWPSQISLQYRSGGSRYHTCGGTLIRQNWVMT
AAHCVDYQKTFRVVAGDHNLSQNDGTEQYVSVQKIVVHPYWNSDNVAAGYDIALLRLAQS
VTLNSYVQLGVLPQEGAILANNSPCYITGWGKTKTNGQLAQTLQQAYLPSVDYAICSSSS
YWGSTVKNTMVCAGGDGVRSGCQGDSGGPLHCLVNGKYSVHGVTSFVSSRGCNVSRKPTV
FTQVSAYISWINNVIASN
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  Blast E-value cutoff:
BDBM50014733
n/a
NameBDBM50014733
Synonyms:2,2-Difluoro-4-[(1-{2-[2-(3-methoxycarbonyl-propionylamino)-propionylamino]-propionyl}-pyrrolidine-2-carbonyl)-amino]-5-methyl-3-oxo-hexanoic acid ethyl ester | CHEMBL340062
TypeSmall organic molecule
Emp. Form.C25H38F2N4O9
Mol. Mass.576.5874
SMILESCCOC(=O)C(F)(F)C(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)CCC(=O)OC)C(C)C
Structure
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