| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cathepsin G |
|---|
| Ligand | BDBM50014743 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_45359 (CHEMBL661895) |
|---|
| Ki | 17000±n/a nM |
|---|
| Citation |  Peet, NP; Burkhart, JP; Angelastro, MR; Giroux, EL; Mehdi, S; Bey, P; Kolb, M; Neises, B; Schirlin, D Synthesis of peptidyl fluoromethyl ketones and peptidyl alpha-keto esters as inhibitors of porcine pancreatic elastase, human neutrophil elastase, and rat and human neutrophil cathepsin G. J Med Chem33:394-407 (1990) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cathepsin G |
|---|
| Name: | Cathepsin G |
|---|
| Synonyms: | CATG_HUMAN | CG | CTSG |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 28860.08 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1469016 |
|---|
| Residue: | 255 |
|---|
| Sequence: | MQPLLLLLAFLLPTGAEAGEIIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVL
TAAHCWGSNINVTLGAHNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRR
NRNVNPVALPRAQEGLRPGTLCTVAGWGRVSMRRGTDTLREVQLRVQRDRQCLRIFGSYD
PRRQICVGDRRERKAAFKGDSGGPLLCNNVAHGIVSYGKSSGVPPEVFTRVSSFLPWIRT
TMRSFKLLDQMETPL
|
|
|
|---|
| BDBM50014743 |
|---|
| n/a |
|---|
| Name | BDBM50014743 |
|---|
| Synonyms: | CHEMBL132171 | N-(1-{2-[2-(1-Benzyl-3,3,3-trifluoro-2-oxo-propylcarbamoyl)-pyrrolidin-1-yl]-1-methyl-2-oxo-ethylcarbamoyl}-ethyl)-succinamic acid methyl ester |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C26H33F3N4O7 |
|---|
| Mol. Mass. | 570.558 |
|---|
| SMILES | COC(=O)CCC(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)C(F)(F)F |
|---|
| Structure | 
|
|---|
Search and Browse
