| Reaction Details |
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 | Report a problem with these data |
| Target | IgA-specific serine endopeptidase autotransporter |
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| Ligand | BDBM50016720 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_88880 |
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| IC50 | >1000000±n/a nM |
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| Citation |  Wood, SG; Lynch, M; Plaut, AG; Burton, J Tetrapeptide inhibitors of the IgA1 proteinases from type I Neisseria gonorrhoeae. J Med Chem32:2407-11 (1989) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| IgA-specific serine endopeptidase autotransporter |
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| Name: | IgA-specific serine endopeptidase autotransporter |
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| Synonyms: | IGA_NEIGO | IgA protease | iga |
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| Type: | PROTEIN |
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| Mol. Mass.: | 169014.39 |
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| Organism: | Neisseria gonorrhoeae |
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| Description: | ChEMBL_88881 |
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| Residue: | 1532 |
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| Sequence: | MKAKRFKINAISLSIFLAYALTPYSEAALVRDDVDYQIFRDFAENKGKFFVGATDLSVKN
KRGQNIGNALSNVPMIDFSVADVNKRIATVVDPQYAVSVKHAKAEVHTFYYGQYNGHNDV
ADKENEYRVVEQNNYEPHKAWGASNLGRLEDYNMARFNKFVTEVAPIAPTDAGGGLDTYK
DKNRFSSFVRIGAGRQLVYEKGVYHQEGNEKGYDLRDLSQAYRYAIAGTPYKDINIDQTM
NTEGLIGFGNHNKQYSAEELKQALSQDALTNYGVLGDSGSPLFAFDKQKNQWVFLGTYDY
WAGYGKKSWQEWNIYKKEFADKIKQHDNAGTVKGNGEHHWKTTGTNSHIGSTAVRLANNE
GDANNGQNVTFEDNGTLVLNQNINQGAGGLFFKGDYTVKGANNDITWLGAGIDVADGKKV
VWQVKNPNGDRLAKIGKGTLEINGTGVNQGQLKVGDGTVILNQKADADKKVQAFSQVGIV
SGRGTLVLNSSNQINPDNLYFGFRGGRLDANGNDLTFEHIRNVDEGARIVNHNTDHASTI
TLTGKSLITNPNSLSVHSIQNDYDEDDYSYYYRPRRPIPQGKDLYYKNYRYYALKSGGRL
NAPMPENGVAENNDWIFMGYTQEEARKNAMNHKNNRRIGDFGGFFDEENGKGHNGALNLN
FNGKSAQKRFLLTGGANLNGKISVTQGNVLLSGRPTPHARDFVNKSSARKDAHFSKNNEV
VFEDDWINRTFKAAEIAVNQSASFSSGRNVSDITANITATDNAKVNLGYKNGDEVCVRSD
YTGYVTCNTGNLSDKALNSFDATRINGNVNLNQNAALVLGKAALWGKIQGQGNSRVSLNQ
HSKWHLTGDSQVHNLSLADSHIHLNNASDAQSANKYHTIKINHLSGNGHFHYLTDLAKNL
GDKVLVKESASGHYQLHVQNKTGEPNQEGLDLFDASSVQDRSRLFVSLANHYVDLGALRY
TIKTENGITRLYNPYAGNGRPVKPAPSPAANTASQAQKATQTDGAQIAKPQNIVVAPPSP
QANQAEEALRQQAKAEQVKRQQAAEAEKVARQKDEEAKRKAAEIARQQEEARKAAELAAK
QKAEAERKARELARQKAEEASHQANAKPKRRRRRAILPRPPAPVFSLDDYDAKDNSESSI
GNLARVIPRMGRELINDYEEIPLEELEDEAEEERRQATQFHSKSRNRRAISSEPSSDEDA
SESVSTSDKHPQDNTELHEKVETAGLQPRAAQPRTQAAAQADAVSTNTNSALSDAMASTQ
SILLDTGAYLTRHIAQKSRADAEKNSVWMSNTGYGRDYASAQYRRFSSKRTQTQIGIDRS
LSENMQIGGVLTYSDSQHTFDQAGGKNTFVQANLYGKYYLNDAWYVAGDIGAGSLRSRLQ
TQQKANFNRTSIQTGLTLGNTLKINQFEIVPSAGIRYSRLSSADYKLGDDSVKVSSMAVK
TLTAGLDFAYRFKVGNLTVKPLLSAAYFANYGKGGVNVGGKSFAYKADNQQQYSAGVALL
YRNVTLNVNGSITKGKQLEKQKSGQIKIQIRF
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| BDBM50016720 |
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| n/a |
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| Name | BDBM50016720 |
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| Synonyms: | 3-Hydroxy-2-[(1-{3-hydroxy-2-[(pyrrolidine-2-carbonyl)-amino]-propionyl}-pyrrolidine-2-carbonyl)-amino]-propionic acid | CHEMBL78355 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H26N4O7 |
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| Mol. Mass. | 386.4002 |
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| SMILES | OC[C@H](NC(=O)[C@H]1CCCN1C(=O)[C@H](CO)NC(=O)[C@H]1CCCN1)C(O)=O |
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| Structure | 
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