| Reaction Details |
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 | Report a problem with these data |
| Target | Vasopressin V2 receptor |
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| Ligand | BDBM50016757 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_214867 |
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| Ki | 4.4±n/a nM |
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| Citation |  Callahan, JF; Ashton-Shue, D; Bryan, HG; Bryan, WM; Heckman, GD; Kinter, LB; McDonald, JE; Moore, ML; Schmidt, DB; Silvestri, JS Structure-activity relationships of novel vasopressin antagonists containing C-terminal diaminoalkanes and (aminoalkyl)guanidines. J Med Chem32:391-6 (1989) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Vasopressin V2 receptor |
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| Name: | Vasopressin V2 receptor |
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| Synonyms: | AVPR2 | V2R_PIG |
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| Type: | PROTEIN |
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| Mol. Mass.: | 40556.17 |
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| Organism: | Sus scrofa |
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| Description: | ChEMBL_214870 |
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| Residue: | 370 |
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| Sequence: | MLRATTSAVPRALSWPAAPGNGSEREPLDDRDPLLARVELALLSTVFVAVALSNGLVLGA
LVRRGRRGRWAPMHVFIGHLCLADLAVALFQVLPQLAWDATYRFRGPDALCRAVKYLQMV
GMYASSYMILAMTLDRHRAICRPMLAYRHGGGARWNRPVLVAWAFSLLLSLPQLFIFAQR
DVGDGSGVLDCWASFAEPWGLRAYVTWIALMVFVAPALGIAACQVLIFREIHTSLVPGPA
ERAGGHRGGRRAGSPREGARVSAAMAKTARMTLVIVAVYVLCWAPFFLVQLWSVWDPKAP
REGPPFVLLMLLASLNSCTNPWIYASFSSSISSELRSLLCCPRRRTPPSLRPQEESCATA
SSFSARDTSS
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| BDBM50016757 |
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| n/a |
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| Name | BDBM50016757 |
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| Synonyms: | 1-[20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzyl)-17-isopropyl-13,16,19,22,25-pentaoxo-7,9-dithia-12,15,18,21,24-pentaaza-spiro[5.20]hexacosane-11-carbonyl]-pyrrolidine-2-carboxylic acid (1-carbamoyl-4-guanidino-butyl)-amide | CHEMBL2370646 |
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| Type | Small organic molecule |
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| Emp. Form. | C52H76N12O10S2 |
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| Mol. Mass. | 1093.364 |
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| SMILES | [#6]-[#6]-[#8]-c1ccc(-[#6]-[#6@H]-2-[#7]-[#6](=O)-[#6]C3([#6]-[#6]-[#6]-[#6]-[#6]3)[#16]-[#6]-[#16]-[#6]-[#6@@H](-[#7]-[#6](=O)-[#6@@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@@H](-[#6]-c3ccccc3)-[#7]-[#6]-2=O)-[#6](-[#6])-[#6])-[#6](=O)-[#7]-2-[#6]-[#6]-[#6]-[#6@H]-2-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](-[#7])=O)cc1 |
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| Structure | 
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