| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Vasopressin V2 receptor |
|---|
| Ligand | BDBM50016756 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_214867 |
|---|
| Ki | 6±n/a nM |
|---|
| Citation |  Callahan, JF; Ashton-Shue, D; Bryan, HG; Bryan, WM; Heckman, GD; Kinter, LB; McDonald, JE; Moore, ML; Schmidt, DB; Silvestri, JS Structure-activity relationships of novel vasopressin antagonists containing C-terminal diaminoalkanes and (aminoalkyl)guanidines. J Med Chem32:391-6 (1989) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Vasopressin V2 receptor |
|---|
| Name: | Vasopressin V2 receptor |
|---|
| Synonyms: | AVPR2 | V2R_PIG |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 40556.17 |
|---|
| Organism: | Sus scrofa |
|---|
| Description: | ChEMBL_214870 |
|---|
| Residue: | 370 |
|---|
| Sequence: | MLRATTSAVPRALSWPAAPGNGSEREPLDDRDPLLARVELALLSTVFVAVALSNGLVLGA
LVRRGRRGRWAPMHVFIGHLCLADLAVALFQVLPQLAWDATYRFRGPDALCRAVKYLQMV
GMYASSYMILAMTLDRHRAICRPMLAYRHGGGARWNRPVLVAWAFSLLLSLPQLFIFAQR
DVGDGSGVLDCWASFAEPWGLRAYVTWIALMVFVAPALGIAACQVLIFREIHTSLVPGPA
ERAGGHRGGRRAGSPREGARVSAAMAKTARMTLVIVAVYVLCWAPFFLVQLWSVWDPKAP
REGPPFVLLMLLASLNSCTNPWIYASFSSSISSELRSLLCCPRRRTPPSLRPQEESCATA
SSFSARDTSS
|
|
|
|---|
| BDBM50016756 |
|---|
| n/a |
|---|
| Name | BDBM50016756 |
|---|
| Synonyms: | CHEMBL265591 | c(Pmp-D-Tyr(Et)-Phe-Val-Asn-Cys)-Pro-NH-(CH2)4-NH-C(=NH)NH2 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C51H75N11O9S2 |
|---|
| Mol. Mass. | 1050.34 |
|---|
| SMILES | CCOc1ccc(C[C@H]2NC(=O)CC3(CCCCC3)SCSC[C@@H](NC(=O)[C@@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@@H](Cc3ccccc3)NC2=O)C(C)C)C(=O)N2CCCC2C(=O)NCCCCNC(N)=N)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
