| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 1B |
|---|
| Ligand | BDBM50001915 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_1795 |
|---|
| Ki | 4.4±n/a nM |
|---|
| Citation |  Martin, GE; Elgin, RJ; Mathiasen, JR; Davis, CB; Kesslick, JM; Baldy, WJ; Shank, RP; DiStefano, DL; Fedde, CL; Scott, MK Activity of aromatic substituted phenylpiperazines lacking affinity for dopamine binding sites in a preclinical test of antipsychotic efficacy. J Med Chem32:1052-6 (1989) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| 5-hydroxytryptamine receptor 1B |
|---|
| Name: | 5-hydroxytryptamine receptor 1B |
|---|
| Synonyms: | 5-HT-1B | 5-HT1B | 5-hydroxytryptamine receptor 1B (5HT1B) | 5HT1B_RAT | 5ht1b | Htr1b | Serotonin 1 (5-HT1) receptor | Serotonin 1B/1D receptor | Serotonin receptor 1B |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 43173.33 |
|---|
| Organism: | Rattus norvegicus (Rat) |
|---|
| Description: | P28564 |
|---|
| Residue: | 386 |
|---|
| Sequence: | MEEQGIQCAPPPPATSQTGVPLANLSHNCSADDYIYQDSIALPWKVLLVALLALITLATT
LSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDF
WLSSDITCCTASIMHLCVIALDRYWAITDAVDYSAKRTPKRAAIMIVLVWVFSISISLPP
FFWRQAKAEEEVLDCFVNTDHVLYTVYSTVGAFYLPTLLLIALYGRIYVEARSRILKQTP
NKTGKRLTRAQLITDSPGSTSSVTSINSRVPEVPSESGSPVYVNQVKVRVSDALLEKKKL
MAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHMAIFDFFNWLGYLNSLI
NPIIYTMSNEDFKQAFHKLIRFKCTG
|
|
|
|---|
| BDBM50001915 |
|---|
| n/a |
|---|
| Name | BDBM50001915 |
|---|
| Synonyms: | 1-(3-chlorophenyl)piperazine | CHEMBL478 | m-Chlorophenylpiperazine | mCPP |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C10H13ClN2 |
|---|
| Mol. Mass. | 196.677 |
|---|
| SMILES | Clc1cccc(c1)N1CCNCC1 |
|---|
| Structure | 
|
|---|
Search and Browse
