| Reaction Details |
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 | Report a problem with these data |
| Target | Platelet-activating factor receptor |
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| Ligand | BDBM50018324 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_154997 |
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| IC50 | 50±n/a nM |
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| Citation |  Tilley, JW; Clader, JW; Zawoiski, S; Wirkus, M; LeMahieu, RA; O'Donnell, M; Crowley, H; Welton, AF Biphenylcarboxamide derivatives as antagonists of platelet-activating factor. J Med Chem32:1814-20 (1989) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Platelet-activating factor receptor |
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| Name: | Platelet-activating factor receptor |
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| Synonyms: | PAF Platelet activating factor | PAF-R | PAFR | PTAFR | PTAFR_HUMAN | Platelet activating factor receptor | Platelet-activating factor receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 39219.60 |
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| Organism: | Homo sapiens (Human) |
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| Description: | PAF Platelet activating factor PTAFR HUMAN::P25105 |
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| Residue: | 342 |
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| Sequence: | MEPHDSSHMDSEFRYTLFPIVYSIIFVLGVIANGYVLWVFARLYPCKKFNEIKIFMVNLT
MADMLFLITLPLWIVYYQNQGNWILPKFLCNVAGCLFFINTYCSVAFLGVITYNRFQAVT
RPIKTAQANTRKRGISLSLVIWVAIVGAASYFLILDSTNTVPDSAGSGNVTRCFEHYEKG
SVPVLIIHIFIVFSFFLVFLIILFCNLVIIRTLLMQPVQQQRNAEVKRRALWMVCTVLAV
FIICFVPHHVVQLPWTLAELGFQDSKFHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKF
RKHLTEKFYSMRSSRKCSRATTDTVTEVVVPFNQIPGNSLKN
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| BDBM50018324 |
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| n/a |
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| Name | BDBM50018324 |
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| Synonyms: | CHEMBL299760 | [1,1';2',1'']Terphenyl-4'-carboxylic acid (1-methyl-4-pyridin-3-yl-butyl)-amide |
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| Type | Small organic molecule |
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| Emp. Form. | C29H28N2O |
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| Mol. Mass. | 420.5454 |
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| SMILES | C[C@H](CCCc1cccnc1)NC(=O)c1ccc(-c2ccccc2)c(c1)-c1ccccc1 |
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| Structure | 
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