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TargetPlatelet activating factor receptor
LigandBDBM50018325
Substrate/Competitorn/a
Meas. Tech.ChEBML_154997
IC50 5±n/a nM
Citation Tilley JWClader JWZawoiski SWirkus MLeMahieu RAO'Donnell MCrowley HWelton AF Biphenylcarboxamide derivatives as antagonists of platelet-activating factor. J Med Chem 32:1814-20 (1989) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Platelet activating factor receptor
Name:Platelet activating factor receptor
Synonyms:PAF Platelet activating factor | PAF-R | Platelet-activating factor receptor
Type:Enzyme Catalytic Domain
Mol. Mass.:39219.60
Organism:Homo sapiens (Human)
Description:PAF Platelet activating factor PTAFR HUMAN::P25105
Residue:342
Sequence:
MEPHDSSHMDSEFRYTLFPIVYSIIFVLGVIANGYVLWVFARLYPCKKFNEIKIFMVNLT
MADMLFLITLPLWIVYYQNQGNWILPKFLCNVAGCLFFINTYCSVAFLGVITYNRFQAVT
RPIKTAQANTRKRGISLSLVIWVAIVGAASYFLILDSTNTVPDSAGSGNVTRCFEHYEKG
SVPVLIIHIFIVFSFFLVFLIILFCNLVIIRTLLMQPVQQQRNAEVKRRALWMVCTVLAV
FIICFVPHHVVQLPWTLAELGFQDSKFHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKF
RKHLTEKFYSMRSSRKCSRATTDTVTEVVVPFNQIPGNSLKN
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50018325
n/a
NameBDBM50018325
Synonyms:CHEMBL53584 | [1,1';2',1'']Terphenyl-4'-carboxylic acid (4-pyridin-3-yl-butyl)-amide
TypeSmall organic molecule
Emp. Form.C28H26N2O
Mol. Mass.406.5188
SMILESO=C(NCCCCc1cccnc1)c1ccc(-c2ccccc2)c(c1)-c1ccccc1
Structure
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