| Reaction Details |
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 | Report a problem with these data |
| Target | Platelet-activating factor receptor |
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| Ligand | BDBM50018352 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_154996 |
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| IC50 | 250±n/a nM |
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| Citation |  Guthrie, RW; Kaplan, GL; Mennona, FA; Tilley, JW; Kierstead, RW; Mullin, JG; LeMahieu, RA; Zawoiski, S; O'Donnell, M; Crowley, H Pentadienyl carboxamide derivatives as antagonists of platelet-activating factor. J Med Chem32:1820-35 (1989) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Platelet-activating factor receptor |
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| Name: | Platelet-activating factor receptor |
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| Synonyms: | PAF Platelet activating factor | PAF-R | PAFR | PTAFR | PTAFR_HUMAN | Platelet activating factor receptor | Platelet-activating factor receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 39219.60 |
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| Organism: | Homo sapiens (Human) |
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| Description: | PAF Platelet activating factor PTAFR HUMAN::P25105 |
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| Residue: | 342 |
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| Sequence: | MEPHDSSHMDSEFRYTLFPIVYSIIFVLGVIANGYVLWVFARLYPCKKFNEIKIFMVNLT
MADMLFLITLPLWIVYYQNQGNWILPKFLCNVAGCLFFINTYCSVAFLGVITYNRFQAVT
RPIKTAQANTRKRGISLSLVIWVAIVGAASYFLILDSTNTVPDSAGSGNVTRCFEHYEKG
SVPVLIIHIFIVFSFFLVFLIILFCNLVIIRTLLMQPVQQQRNAEVKRRALWMVCTVLAV
FIICFVPHHVVQLPWTLAELGFQDSKFHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKF
RKHLTEKFYSMRSSRKCSRATTDTVTEVVVPFNQIPGNSLKN
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| BDBM50018352 |
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| n/a |
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| Name | BDBM50018352 |
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| Synonyms: | 5,5-Bis-(4-methoxy-phenyl)-penta-2,4-dienoic acid (4-pyridin-3-ylmethyl-phenyl)-amide | CHEMBL54106 |
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| Type | Small organic molecule |
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| Emp. Form. | C31H28N2O3 |
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| Mol. Mass. | 476.5656 |
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| SMILES | [#6]-[#8]-c1ccc(cc1)-[#6](=[#6]/[#6]=[#6]/[#6](=O)-[#7]-c1ccc(-[#6]-c2cccnc2)cc1)\c1ccc(-[#8]-[#6])cc1 |
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| Structure | 
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