| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Platelet-activating factor receptor |
|---|
| Ligand | BDBM50018386 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_154996 |
|---|
| IC50 | 60±n/a nM |
|---|
| Citation |  Guthrie, RW; Kaplan, GL; Mennona, FA; Tilley, JW; Kierstead, RW; Mullin, JG; LeMahieu, RA; Zawoiski, S; O'Donnell, M; Crowley, H Pentadienyl carboxamide derivatives as antagonists of platelet-activating factor. J Med Chem32:1820-35 (1989) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Platelet-activating factor receptor |
|---|
| Name: | Platelet-activating factor receptor |
|---|
| Synonyms: | PAF Platelet activating factor | PAF-R | PAFR | PTAFR | PTAFR_HUMAN | Platelet activating factor receptor | Platelet-activating factor receptor |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 39219.60 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | PAF Platelet activating factor PTAFR HUMAN::P25105 |
|---|
| Residue: | 342 |
|---|
| Sequence: | MEPHDSSHMDSEFRYTLFPIVYSIIFVLGVIANGYVLWVFARLYPCKKFNEIKIFMVNLT
MADMLFLITLPLWIVYYQNQGNWILPKFLCNVAGCLFFINTYCSVAFLGVITYNRFQAVT
RPIKTAQANTRKRGISLSLVIWVAIVGAASYFLILDSTNTVPDSAGSGNVTRCFEHYEKG
SVPVLIIHIFIVFSFFLVFLIILFCNLVIIRTLLMQPVQQQRNAEVKRRALWMVCTVLAV
FIICFVPHHVVQLPWTLAELGFQDSKFHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKF
RKHLTEKFYSMRSSRKCSRATTDTVTEVVVPFNQIPGNSLKN
|
|
|
|---|
| BDBM50018386 |
|---|
| n/a |
|---|
| Name | BDBM50018386 |
|---|
| Synonyms: | 5,5-Bis-(4-methoxy-phenyl)-penta-2,4-dienoic acid (1-cyclopropyl-4-pyridin-3-yl-butyl)-amide | CHEMBL53029 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C31H34N2O3 |
|---|
| Mol. Mass. | 482.6133 |
|---|
| SMILES | [#6]-[#8]-c1ccc(cc1)-[#6](=[#6]\[#6]=[#6]\[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-c1cccnc1)-[#6]-1-[#6]-[#6]-1)\c1ccc(-[#8]-[#6])cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
