| Reaction Details |
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 | Report a problem with these data |
| Target | Platelet-activating factor receptor |
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| Ligand | BDBM50011671 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_154996 (CHEMBL767100) |
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| IC50 | 40±n/a nM |
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| Citation |  Guthrie, RW; Kaplan, GL; Mennona, FA; Tilley, JW; Kierstead, RW; Mullin, JG; LeMahieu, RA; Zawoiski, S; O'Donnell, M; Crowley, H Pentadienyl carboxamide derivatives as antagonists of platelet-activating factor. J Med Chem32:1820-35 (1989) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Platelet-activating factor receptor |
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| Name: | Platelet-activating factor receptor |
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| Synonyms: | PAF Platelet activating factor | PAF-R | PAFR | PTAFR | PTAFR_HUMAN | Platelet activating factor receptor | Platelet-activating factor receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 39219.60 |
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| Organism: | Homo sapiens (Human) |
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| Description: | PAF Platelet activating factor PTAFR HUMAN::P25105 |
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| Residue: | 342 |
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| Sequence: | MEPHDSSHMDSEFRYTLFPIVYSIIFVLGVIANGYVLWVFARLYPCKKFNEIKIFMVNLT
MADMLFLITLPLWIVYYQNQGNWILPKFLCNVAGCLFFINTYCSVAFLGVITYNRFQAVT
RPIKTAQANTRKRGISLSLVIWVAIVGAASYFLILDSTNTVPDSAGSGNVTRCFEHYEKG
SVPVLIIHIFIVFSFFLVFLIILFCNLVIIRTLLMQPVQQQRNAEVKRRALWMVCTVLAV
FIICFVPHHVVQLPWTLAELGFQDSKFHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKF
RKHLTEKFYSMRSSRKCSRATTDTVTEVVVPFNQIPGNSLKN
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| BDBM50011671 |
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| n/a |
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| Name | BDBM50011671 |
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| Synonyms: | (2E,4E)-5-(4-Methoxy-phenyl)-deca-2,4-dienoic acid ((R)-1-methyl-4-pyridin-3-yl-butyl)-amide | 5-(4-Methoxy-phenyl)-deca-2,4-dienoic acid (1-methyl-4-pyridin-3-yl-butyl)-amide | CHEMBL277245 | Ro-24-0238 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H36N2O2 |
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| Mol. Mass. | 420.5869 |
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| SMILES | CCCCC\C(=C/C=C/C(=O)N[C@H](C)CCCc1cccnc1)c1ccc(OC)cc1 |
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| Structure | 
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