Ki Summary new BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetPlatelet activating factor receptor
LigandBDBM50018392
Substrate/Competitorn/a
Meas. Tech.ChEMBL_154996
IC50 4±n/a nM
Citation Guthrie RWKaplan GLMennona FATilley JWKierstead RWMullin JGLeMahieu RAZawoiski SO'Donnell MCrowley H Pentadienyl carboxamide derivatives as antagonists of platelet-activating factor. J Med Chem 32:1820-35 (1989) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Platelet activating factor receptor
Name:Platelet activating factor receptor
Synonyms:PAF Platelet activating factor | PAF-R | Platelet-activating factor receptor
Type:Enzyme Catalytic Domain
Mol. Mass.:39219.60
Organism:Homo sapiens (Human)
Description:PAF Platelet activating factor PTAFR HUMAN::P25105
Residue:342
Sequence:
MEPHDSSHMDSEFRYTLFPIVYSIIFVLGVIANGYVLWVFARLYPCKKFNEIKIFMVNLT
MADMLFLITLPLWIVYYQNQGNWILPKFLCNVAGCLFFINTYCSVAFLGVITYNRFQAVT
RPIKTAQANTRKRGISLSLVIWVAIVGAASYFLILDSTNTVPDSAGSGNVTRCFEHYEKG
SVPVLIIHIFIVFSFFLVFLIILFCNLVIIRTLLMQPVQQQRNAEVKRRALWMVCTVLAV
FIICFVPHHVVQLPWTLAELGFQDSKFHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKF
RKHLTEKFYSMRSSRKCSRATTDTVTEVVVPFNQIPGNSLKN
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50018392
n/a
NameBDBM50018392
Synonyms:5-(4-Methoxy-phenyl)-5-phenyl-penta-2,4-dienoic acid (1-methyl-4-pyridin-3-yl-butyl)-amide | CHEMBL52925
TypeSmall organic molecule
Emp. Form.C28H30N2O2
Mol. Mass.426.55
SMILESCOc1ccc(cc1)C(=C/C=C/C(=O)N[C@H](C)CCCc1cccnc1)\c1ccccc1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: