| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Squalene monooxygenase |
|---|
| Ligand | BDBM50018524 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_201927 (CHEMBL808214) |
|---|
| Ki | 950000±n/a nM |
|---|
| Citation |  Sen, SE; Prestwich, GD Squalene analogues containing isopropylidene mimics as potential inhibitors of pig liver squalene epoxidase and oxidosqualene cyclase. J Med Chem32:2152-8 (1989) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Squalene monooxygenase |
|---|
| Name: | Squalene monooxygenase |
|---|
| Synonyms: | ERG1 | ERG1_HUMAN | SE | SQLE | Squalene epoxidase |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 63936.94 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_201924 |
|---|
| Residue: | 574 |
|---|
| Sequence: | MWTFLGIATFTYFYKKFGDFITLANREVLLCVLVFLSLGLVLSYRCRHRNGGLLGRQQSG
SQFALFSDILSGLPFIGFFWAKSPPESENKEQLEARRRRKGTNISETSLIGTAACTSTSS
QNDPEVIIVGAGVLGSALAAVLSRDGRKVTVIERDLKEPDRIVGEFLQPGGYHVLKDLGL
GDTVEGLDAQVVNGYMIHDQESKSEVQIPYPLSENNQVQSGRAFHHGRFIMSLRKAAMAE
PNAKFIEGVVLQLLEEDDVVMGVQYKDKETGDIKELHAPLTVVADGLFSKFRKSLVSNKV
SVSSHFVGFLMKNAPQFKANHAELILANPSPVLIYQISSSETRVLVDIRGEMPRNLREYM
VEKIYPQIPDHLKEPFLEATDNSHLRSMPASFLPPSSVKKRGVLLLGDAYNMRHPLTGGG
MTVAFKDIKLWRKLLKGIPDLYDDAAIFEAKKSFYWARKTSHSFVVNILAQALYELFSAT
DDSLHQLRKACFLYFKLGGECVAGPVGLLSVLSPNPLVLIGHFFAVAIYAVYFCFKSEPW
ITKPRALLSSGAVLYKACSVIFPLIYSEMKYMVH
|
|
|
|---|
| BDBM50018524 |
|---|
| n/a |
|---|
| Name | BDBM50018524 |
|---|
| Synonyms: | 6,10,15,19,23-Pentamethyl-tetracosa-6,10,14,18,22-pentaen-1-yn-3-ol | CHEMBL70015 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C29H46O |
|---|
| Mol. Mass. | 410.6749 |
|---|
| SMILES | [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]-[#6](-[#8])C#C |
|---|
| Structure | 
|
|---|
Search and Browse
