| Reaction Details |
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 | Report a problem with these data |
| Target | Thromboxane A2 receptor |
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| Ligand | BDBM50279755 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_209431 (CHEMBL814288) |
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| IC50 | 7.4±n/a nM |
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| Citation |  Shiraishi, M; Kato, K; Terao, S; Ashida, Y; Terashita, Z; Kito, G Quinones. 4. Novel eicosanoid antagonists: synthesis and pharmacological evaluation. J Med Chem32:2214-21 (1989) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Thromboxane A2 receptor |
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| Name: | Thromboxane A2 receptor |
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| Synonyms: | Prostanoid TP receptor | TA2R_HUMAN | TBXA2R | TXA2-R | Thromboxane | Thromboxane A2 receptor | Thromboxane Beta |
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| Type: | Enyzme |
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| Mol. Mass.: | 37445.28 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21731 |
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| Residue: | 343 |
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| Sequence: | MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTR
SSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPL
LLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPG
SWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSE
VEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWN
QILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
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| BDBM50279755 |
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| n/a |
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| Name | BDBM50279755 |
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| Synonyms: | 7-Phenyl-7-(2,4,5-trimethyl-3,6-dioxo-cyclohexa-1,4-dienyl)-heptanoic acid | CHEMBL70972 | Seratrodast |
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| Type | Small organic molecule |
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| Emp. Form. | C22H26O4 |
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| Mol. Mass. | 354.4394 |
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| SMILES | Cc1c(C)c(O)c(C(=CCCCCC(O)=O)c2ccccc2)c(C)c1O |w:8.8| |
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| Structure | 
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