| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-1A adrenergic receptor |
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| Ligand | BDBM50018739 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_33091 |
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| Ki | 16±n/a nM |
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| Citation |  Huff, JR; Baldwin, JJ; deSolms, SJ; Guare, JP; Hunt, CA; Randall, WC; Sanders, WS; Smith, SJ; Vacca, JP; Zrada, MM Structure-affinity relationships of arylquinolizines at alpha-adrenoceptors. J Med Chem31:641-5 (1988) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Alpha-1A adrenergic receptor |
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| Name: | Alpha-1A adrenergic receptor |
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| Synonyms: | ADA1A_BOVIN | ADRA1A | ADRA1C | Alpha 1A-adrenoceptor | Alpha 1A-adrenoreceptor | Alpha-1C adrenergic receptor | Cerebral cortex alpha adrenergic receptor | adrenergic Alpha1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 51492.08 |
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| Organism: | CALF |
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| Description: | adrenergic Alpha1 0 CALF |
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| Residue: | 466 |
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| Sequence: | MVFLSGNASDSSNCTHPPPPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSV
THYYIVNLAVADLLLTSTVLPFSAIFEILGYWAFGRVFCNVWAAVDVLCCTASIMGLCII
SIDRYIGVSYPLRYPTIVTQKRGLMALLCVWALSLVISIGPLFGWRQPAPEDETICQINE
EPGYVLFSALGSFYVPLTIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKN
AQVGGSGVTSAKNKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPD
FRPSETVFKIAFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLRRKQSSKHTLGYTL
HAPSHVLEGQHKDLVRIPVGSAETFYKISKTDGVCEWKIFSSLPRGSARMAVARDPSACT
TARVRSKSFLQVCCCLGPSTPSHGENHQIPTIKIHTISLSENGEEV
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|
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| BDBM50018739 |
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| n/a |
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| Name | BDBM50018739 |
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| Synonyms: | 1,3,4,5,6,11b-Hexahydro-2H-11-thia-4a-aza-benzo[a]fluorene | CHEMBL346492 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H17NS |
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| Mol. Mass. | 243.367 |
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| SMILES | C1CCN2CCc3c(sc4ccccc34)C2C1 |
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| Structure | 
|
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