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TargetMu-type opioid receptor
LigandBDBM50452249
Substrate/Competitorn/a
Meas. Tech.ChEBML_146984
IC50 8890±n/a nM
Citation Gairin, JEMazarguil, HAlvinerie, PSaint-Pierre, SMeunier, JCCros, J Synthesis and biological activities of dynorphin A analogues with opioid antagonist properties. J Med Chem29:1913-7 (1986) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Mu-type opioid receptor
Name:Mu-type opioid receptor
Synonyms:M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO
Type:Enzyme Catalytic Domain
Mol. Mass.:11165.58
Organism:GUINEA PIG
Description:P97266
Residue:98
Sequence:
YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSI
FTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50452249
n/a
NameBDBM50452249
Synonyms:CHEMBL2373012
TypeSmall organic molecule
Emp. Form.C77H109N23O13
Mol. Mass.1564.8357
SMILESCC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@@H]1C(=O)N[C@@H](CCCCN)C(O)=O |wU:72.75,4.4,86.91,61.64,104.110,wD:100.107,23.36,50.53,8.16,37.40,(25.09,-20.82,;25.59,-19.36,;24.58,-18.2,;27.1,-19.07,;27.61,-17.61,;29.12,-17.32,;30.13,-18.49,;29.62,-19.94,;31.64,-18.2,;32.14,-16.74,;31.14,-15.58,;31.64,-14.12,;30.63,-12.96,;29.12,-13.25,;28.62,-14.7,;29.62,-15.87,;32.65,-19.36,;34.16,-19.07,;34.66,-17.61,;35.17,-20.23,;36.68,-19.94,;37.69,-21.11,;37.18,-22.56,;39.2,-20.82,;40.21,-21.98,;39.7,-23.44,;38.23,-23.88,;38.2,-25.42,;39.66,-25.93,;40.26,-27.35,;41.78,-27.54,;42.71,-26.31,;42.11,-24.89,;40.59,-24.7,;39.7,-19.36,;38.7,-18.2,;37.18,-18.49,;39.2,-16.74,;40.71,-16.45,;38.19,-15.58,;38.7,-14.12,;37.69,-12.96,;38.19,-11.5,;39.7,-11.21,;40.21,-9.76,;40.71,-12.38,;40.21,-13.83,;26.6,-16.45,;27.1,-15,;25.09,-16.74,;24.08,-15.58,;24.58,-14.12,;26.09,-13.83,;26.6,-12.38,;28.11,-12.09,;28.62,-10.63,;30.13,-10.34,;27.61,-9.47,;22.57,-15.87,;22.06,-17.32,;21.56,-14.7,;20.05,-15,;19.54,-16.45,;18.03,-16.74,;17.53,-18.2,;16.01,-18.49,;15.51,-19.94,;14,-20.23,;16.52,-21.11,;19.04,-13.83,;19.54,-12.38,;17.53,-14.12,;16.52,-12.96,;17.02,-11.5,;16.01,-10.34,;14.48,-10.47,;13.88,-9.05,;15.04,-8.04,;15.07,-6.5,;16.42,-5.76,;17.74,-6.56,;17.71,-8.1,;16.36,-8.84,;15,-13.25,;14.5,-14.7,;14,-12.09,;12.48,-12.38,;11.98,-13.83,;10.47,-14.12,;9.96,-15.58,;8.45,-15.87,;7.95,-17.32,;6.44,-17.61,;8.96,-18.49,;11.48,-11.21,;11.98,-9.76,;9.96,-11.5,;9.31,-12.9,;7.78,-12.71,;7.49,-11.19,;8.84,-10.45,;9.03,-8.92,;10.45,-8.32,;7.8,-7.99,;7.99,-6.47,;6.76,-5.54,;6.95,-4.01,;5.73,-3.08,;5.92,-1.55,;4.69,-.62,;9.41,-5.87,;10.64,-6.8,;9.6,-4.34,)|
Structure
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