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TargetDopamine D2 receptor/Serotonin 2 (5-HT2) receptor
LigandBDBM50020177
Substrate/Competitorn/a
Meas. Tech.ChEBML_63037
Ki 0.680000±n/a nM
Citation van Wijngaarden IKruse CGvan der Heyden JATulp MT 2-Phenylpyrroles as conformationally restricted benzamide analogues. A new class of potential antipsychotics. 2. J Med Chem 31:1934-40 (1988) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor
Name:Dopamine D2 receptor and Serotonin 2a receptor (D2 and 5HT2a)
Synonyms:DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DOPAMINE D2/D4 | DRD2 | Dopamine D2 receptor | Dopamine2-like
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:50931.60
Organism:Rattus norvegicus (rat)
Description:Receptor binding assays were performed using rat striatal membranes.
Residue:444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMS
RRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNS
AVNPIIYTTFNIEFRKAFMKILHC
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  Blast E-value cutoff:
BDBM50020177
n/a
NameBDBM50020177
Synonyms:1-(3,4-Dihydro-2H-benzo[b][1,4]dioxepin-6-yl)-4-(5-phenyl-1H-pyrrol-2-ylmethyl)-piperazine | CHEMBL61294
TypeSmall organic molecule
Emp. Form.C24H27N3O2
Mol. Mass.389.4901
SMILESC(N1CCN(CC1)c1cccc2OCCCOc12)c1ccc([nH]1)-c1ccccc1
Structure
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