| Reaction Details |
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 | Report a problem with these data |
| Target | Vasopressin V2 receptor |
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| Ligand | BDBM50020656 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_215034 |
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| Ki | 9.40±n/a nM |
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| Citation |  Huffman, WF; Ali, FE; Bryan, WM; Callahan, JF; Moore, ML; Silvestri, JS; Yim, NC; Kinter, LB; McDonald, JE; Ashton-Shue, D Novel vasopressin analogues that help define a minimum effective antagonist pharmacophore. J Med Chem28:1759-60 (1986) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Vasopressin V2 receptor |
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| Name: | Vasopressin V2 receptor |
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| Synonyms: | AVPR2 | V2R_PIG |
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| Type: | PROTEIN |
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| Mol. Mass.: | 40556.17 |
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| Organism: | Sus scrofa |
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| Description: | ChEMBL_214870 |
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| Residue: | 370 |
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| Sequence: | MLRATTSAVPRALSWPAAPGNGSEREPLDDRDPLLARVELALLSTVFVAVALSNGLVLGA
LVRRGRRGRWAPMHVFIGHLCLADLAVALFQVLPQLAWDATYRFRGPDALCRAVKYLQMV
GMYASSYMILAMTLDRHRAICRPMLAYRHGGGARWNRPVLVAWAFSLLLSLPQLFIFAQR
DVGDGSGVLDCWASFAEPWGLRAYVTWIALMVFVAPALGIAACQVLIFREIHTSLVPGPA
ERAGGHRGGRRAGSPREGARVSAAMAKTARMTLVIVAVYVLCWAPFFLVQLWSVWDPKAP
REGPPFVLLMLLASLNSCTNPWIYASFSSSISSELRSLLCCPRRRTPPSLRPQEESCATA
SSFSARDTSS
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| BDBM50020656 |
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| n/a |
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| Name | BDBM50020656 |
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| Synonyms: | 1-[19-Benzyl-13-carbamoylmethyl-22-(4-ethoxy-benzyl)-16-isopropyl-12,15,18,21,24-pentaoxo-7,8-dithia-11,14,17,20,23-pentaaza-spiro[5.19]pentacosane-10-carbonyl]-pyrrolidine-2-carboxylic acid (5-amino-1-carbamoyl-pentyl)-amide | CHEMBL262499 |
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| Type | Small organic molecule |
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| Emp. Form. | C51H74N10O10S2 |
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| Mol. Mass. | 1051.324 |
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| SMILES | CCOc1ccc(C[C@H]2NC(=O)CC3(CCCCC3)SSC[C@@H](NC(=O)[C@@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@@H](Cc3ccccc3)NC2=O)C(C)C)C(=O)N2CCC[C@H]2C(=O)N[C@H](CCCCN)C(N)=O)cc1 |
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| Structure | 
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