| Reaction Details |
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 | Report a problem with these data |
| Target | Pepsin A |
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| Ligand | BDBM50022293 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_154015 |
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| Ki | 2.5±n/a nM |
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| Citation |  Holladay, MW; Salituro, FG; Rich, DH Synthetic and enzyme inhibition studies of pepstatin analogues containing hydroxyethylene and ketomethylene dipeptide isosteres. J Med Chem30:374-83 (1987) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Pepsin A |
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| Name: | Pepsin A |
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| Synonyms: | PEPA_PIG | PGA | Pepsin | Pepsin A precursor |
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| Type: | Enzyme |
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| Mol. Mass.: | 41232.87 |
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| Organism: | Porcine |
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| Description: | n/a |
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| Residue: | 385 |
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| Sequence: | MKWLLLLSLVVLSECLVKVPLVRKKSLRQNLIKNGKLKDFLKTHKHNPASKYFPEAAALI
GDEPLENYLDTEYFGTIGIGTPAQDFTVIFDTGSSNLWVPSVYCSSLACSDHNQFNPDDS
STFEATSQELSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDGIL
GLAYPSISASGATPVFDNLWDQGLVSQDLFSVYLSSNDDSGSVVLLGGIDSSYYTGSLNW
VPVSVEGYWQITLDSITMDGETIACSGGCQAIVDTGTSLLTGPTSAIANIQSDIGASENS
DGEMVISCSSIDSLPDIVFTINGVQYPLSPSAYILQDDDSCTSGFEGMDVPTSSGELWIL
GDVFIRQYYTVFDRANNKVGLAPVA
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| BDBM50022293 |
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| n/a |
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| Name | BDBM50022293 |
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| Synonyms: | CHEMBL124266 | N-(2-Hydroxy-1-isobutyl-4-{1-[1-(3-methyl-butylcarbamoyl)-ethylcarbamoyl]-2-phenyl-ethylamino}-butyl)-3-methyl-2-(3-methyl-butyrylamino)-butyramide |
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| Type | Small organic molecule |
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| Emp. Form. | C34H58N4O5 |
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| Mol. Mass. | 602.8481 |
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| SMILES | CC(C)CCNC(=O)C(C)NC(=O)C(C[C@H](O)[C@H](CC(C)C)NC(=O)C(NC(=O)CC(C)C)C(C)C)Cc1ccccc1 |
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| Structure | 
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