| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-lactamase TEM |
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| Ligand | BDBM50022790 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_40718 |
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| Ki | 20000±n/a nM |
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| Citation |  Joyeau, R; Molines, H; Labia, R; Wakselman, M N-aryl 3-halogenated azetidin-2-ones and benzocarbacephems, inhibitors of beta-lactamases. J Med Chem31:370-4 (1988) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-lactamase TEM |
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| Name: | Beta-lactamase TEM |
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| Synonyms: | BLAT_ECOLX | Bacterial beta-lactamase TEM | Beta-lactamase (TEM-1) | Beta-lactamase TEM | Beta-lactamase TEM-1 | Beta-lactamase TEM-1b | Beta-lactamase TEM1D | Beta-lactamase TEM1E | Beta-lactamase TEM1F | TEM beta lactamase | TEM extended-spectrum beta-lactamase | TEM-1 beta-lactamase | bla |
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| Type: | Enzyme |
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| Mol. Mass.: | 31512.33 |
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| Organism: | Escherichia coli |
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| Description: | P62593 |
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| Residue: | 286 |
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| Sequence: | MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRP
EERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREL
CSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTM
PAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGS
RGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
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|
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| BDBM50022790 |
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| n/a |
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| Name | BDBM50022790 |
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| Synonyms: | 1-Oxo-2,2a,3,4-tetrahydro-1H-azeto[1,2-a]quinoline-7-carboxylic acid | CHEMBL333494 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H11NO3 |
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| Mol. Mass. | 217.2206 |
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| SMILES | OC(=O)c1ccc2CCC3CC(=O)N3c2c1 |
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| Structure | 
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