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TargetLeukocyte elastase
LigandBDBM50025849
Substrate/Competitorn/a
Meas. Tech.ChEMBL_96636
Ki 1800000±n/a nM
Citation Groutas WCAbrams WRTheodorakis MCKasper AMRude SABadger RCOcain TDMiller KEMoi MKBrubaker MJ Amino acid derived latent isocyanates: irreversible inactivation of porcine pancreatic elastase and human leukocyte elastase. J Med Chem 28:204-9 (1985) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Leukocyte elastase
Name:Leukocyte elastase
Synonyms:Bone marrow serine protease | Chymotrypsin | Coagulation factor X | Elastase | Elastase-2 | HLE | Human leukocyte elastase | Leukocyte elastase (HLE) | Medullasin | Neutrophil elastase | Neutrophil elastase (HNE) | Neutrophil elastase (NE) | PMN elastase | Thrombin | Trypsin
Type:Enzyme
Mol. Mass.:28532.38
Organism:Homo sapiens (Human)
Description:P08246
Residue:267
Sequence:
MTLGRRLACLFLACVLPALLLGGTALASEIVGGRRARPHAWPFMVSLQLRGGHFCGATLI
APNFVMSAAHCVANVNVRAVRVVLGAHNLSRREPTRQVFAVQRIFENGYDPVNLLNDIVI
LQLNGSATINANVQVAQLPAQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTSL
CRRSNVCTLVRGRQAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVN
WIDSIIQRSEDNPCPHPRDPDPASRTH
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  Blast E-value cutoff:
BDBM50025849
n/a
NameBDBM50025849
Synonyms:2-[(Imidazole-1-carbonyl)-amino]-3-methyl-butyric acid methyl ester | CHEMBL291635
TypeSmall organic molecule
Emp. Form.C10H15N3O3
Mol. Mass.225.2444
SMILESCOC(=O)[C@@H](NC(=O)n1ccnc1)C(C)C
Structure
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