| Reaction Details |
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 | Report a problem with these data |
| Target | Dihydropteridine reductase |
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| Ligand | BDBM50025878 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_50920 (CHEMBL664148) |
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| Ki | 3300±n/a nM |
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| Citation |  Gessner, W; Brossi, A; Shen, R; Abell, CW Synthesis and dihydropteridine reductase inhibitory effects of potential metabolites of the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. J Med Chem28:311-7 (1985) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Dihydropteridine reductase |
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| Name: | Dihydropteridine reductase |
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| Synonyms: | DHPR_RAT | Dhpr | Qdpr |
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| Type: | PROTEIN |
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| Mol. Mass.: | 25554.95 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_54067 |
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| Residue: | 241 |
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| Sequence: | MAASGEARRVLVYGGRGALGSRCVQAFRARNWWVASIDVVENEEASASVIVKMTDSFTEQ
ADQVTAEVGKLLGDQKVDAILCVAGGWAGGNAKSKSLFKNCDLMWKQSIWTSTISSHLAT
KHLKEGGLLTLAGAKAALDGTPGMIGYGMAKGAVHQLCQSLAGKNSGMPSGAAAIAVLPV
TLDTPMNRKSMPEADFSSWTPLEFLVETFHDWITGNKRPNSGSLIQVVTTDGKTELTPAY
F
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| BDBM50025878 |
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| n/a |
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| Name | BDBM50025878 |
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| Synonyms: | 4-(1-Methyl-1,2,3,6-tetrahydro-pyridin-4-yl)-benzene-1,2-diol | CHEMBL323998 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H15NO2 |
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| Mol. Mass. | 205.253 |
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| SMILES | CN1CCC(=CC1)c1ccc(O)c(O)c1 |c:4| |
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| Structure | 
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