| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Pepsin A |
|---|
| Ligand | BDBM50025901 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_154011 |
|---|
| Ki | 2.5±n/a nM |
|---|
| Citation |  Rich, DH Pepstatin-derived inhibitors of aspartic proteinases. A close look at an apparent transition-state analogue inhibitor. J Med Chem28:263-73 (1985) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Pepsin A |
|---|
| Name: | Pepsin A |
|---|
| Synonyms: | PEPA_PIG | PGA | Pepsin | Pepsin A precursor |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 41232.87 |
|---|
| Organism: | Porcine |
|---|
| Description: | n/a |
|---|
| Residue: | 385 |
|---|
| Sequence: | MKWLLLLSLVVLSECLVKVPLVRKKSLRQNLIKNGKLKDFLKTHKHNPASKYFPEAAALI
GDEPLENYLDTEYFGTIGIGTPAQDFTVIFDTGSSNLWVPSVYCSSLACSDHNQFNPDDS
STFEATSQELSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDGIL
GLAYPSISASGATPVFDNLWDQGLVSQDLFSVYLSSNDDSGSVVLLGGIDSSYYTGSLNW
VPVSVEGYWQITLDSITMDGETIACSGGCQAIVDTGTSLLTGPTSAIANIQSDIGASENS
DGEMVISCSSIDSLPDIVFTINGVQYPLSPSAYILQDDDSCTSGFEGMDVPTSSGELWIL
GDVFIRQYYTVFDRANNKVGLAPVA
|
|
|
|---|
| BDBM50025901 |
|---|
| n/a |
|---|
| Name | BDBM50025901 |
|---|
| Synonyms: | 4-Hydroxy-7-methyl-5-[3-methyl-2-(3-methyl-butyrylamino)-butyrylamino]-2-phenyl-octanoic acid [1-methyl-2-(4-methyl-pentanoylamino)-2-oxo-ethyl]-amide | CHEMBL90576 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C34H56N4O6 |
|---|
| Mol. Mass. | 616.8316 |
|---|
| SMILES | CC(C)CCC(=O)NC(=O)[C@H](C)NC(=O)[C@@H](CC(O)[C@@H](CC(C)C)NC(=O)[C@H](NC(=O)CC(C)C)C(C)C)c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
