| Reaction Details |
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 | Report a problem with these data |
| Target | Choline O-acetyltransferase |
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| Ligand | BDBM50026470 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_27377 (CHEMBL642410) |
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| Ki | 13000000±n/a nM |
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| Citation |  Cohen, SG; Chishti, SB; Elkind, JL; Reese, H; Cohen, JB Effects of charge, volume, and surface on binding of inhibitor and substrate moieties to acetylcholinesterase. J Med Chem28:1309-13 (1985) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Choline O-acetyltransferase |
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| Name: | Choline O-acetyltransferase |
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| Synonyms: | CLAT_RAT | Chat | Choline Acetyltransferase | Choline O-acetyltransferase | Choline acetylase |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 71875.58 |
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| Organism: | RAT |
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| Description: | Choline Acetyltransferase 0 RAT::P32738 |
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| Residue: | 640 |
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| Sequence: | MPILEKAPQKMPVKASSWEELDLPKLPVPPLQQTLATYLQCMQHLVPEEQFRKSQAIVKR
FGAPGGLGETLQEKLLERQEKTANWVSEYWLNDMYLNNRLALPVNSSPAVIFARQHFQDT
NDQLRFAACLISGVLSYKTLLDSHSLPTDWAKGQLSGQPLCMKQYYRLFSSYRLPGHTQD
TLVAQKSSIMPEPEHVIVACCNQFFVLDVVINFRRLSEGDLFTQLRKIVKMASNEDERLP
PIGLLTSDGRSEWAKARTVLLKDSTNRDSLDMIERCICLVCLDGPGTGELSDTHRALQLL
HGGGCSLNGANRWYDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQCTEHLLKHMMTSNKKL
VRADSVSELPAPRRLRLKCSPETQGHLASSAEKLQRIVKNLDFIVYKFDNYGKTFIKKQK
YSPDGFIQVALQLAYYRLYQRLVPTYESASIRRFQEGRVDNIRSATPEALAFVQAMTDHK
AAMPASEKLQLLQTAMQAHKQYTVMAITGMAIDNHLLALRELARDLCKEPPEMFMDETYL
MSNRFVLSTSQVPTTMEMFCCYGPVVPNGNGACYNPQPEAITFCISSFHSCKETSSVEFA
EAVGASLVDMRDLCSSRQPADSKPPAPKEKARGPSQAKQS
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| BDBM50026470 |
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| n/a |
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| Name | BDBM50026470 |
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| Synonyms: | (2-Hydroxy-ethyl)-dimethyl-sulfonium; iodide | CHEMBL25355 |
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| Type | Small organic molecule |
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| Emp. Form. | C4H11IOS |
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| Mol. Mass. | 234.099 |
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| SMILES | CS(C)(I)CCO |
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| Structure | 
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