| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-2A adrenergic receptor |
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| Ligand | BDBM50027013 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_33031 |
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| Ki | 11±n/a nM |
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| Citation |  Saari, WS; Halczenko, W; King, SW; Huff, JR; Guare, JP; Hunt, CA; Randall, WC; Anderson, PS; Lotti, VJ; Taylor, DA Pyridinylpiperazines, a new class of selective alpha 2-adrenoceptor antagonists. J Med Chem26:1696-701 (1984) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Alpha-2A adrenergic receptor |
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| Name: | Alpha-2A adrenergic receptor |
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| Synonyms: | ADA2A_BOVIN | ADRA2A | Alpha-2A adrenergic receptor | Alpha-2A adrenoceptor | Alpha-2A adrenoreceptor | Alpha-2AAR | Alpha-2D adrenergic receptor | Alpha-2Da adrenergic receptor | Cerebral cortex alpha adrenergic receptor | adrenergic Alpha2A | adrenergic Alpha2D |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 49275.13 |
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| Organism: | BOVINE |
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| Description: | adrenergic Alpha2 0 BOVINE::Q28838 |
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| Residue: | 452 |
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| Sequence: | MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLFTVFGNVLVIIAVFT
SRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSS
IVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIVTVWVISAVISFPPLISFEKKRGRSG
QPSAEPRCEINDQKWYVISSSIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDATA
AELPGSAERRPNGLGPERGGVGPVGAEVESLQVQLNGAPGEPAPAGAGADALDLEESSSS
EHAERPPGSRRSERGPRAKGKARASQVKPGDSLPRRGPGATGLGAPTAGPAEERSGGGAK
ASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAIGCPVPPTLFKFFFWFGYCN
SSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV
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| BDBM50027013 |
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| n/a |
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| Name | BDBM50027013 |
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| Synonyms: | 1-(3-Bromo-pyridin-2-yl)-piperazine | CHEMBL295921 |
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| Type | Small organic molecule |
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| Emp. Form. | C9H12BrN3 |
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| Mol. Mass. | 242.116 |
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| SMILES | Brc1cccnc1N1CCNCC1 |
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| Structure | 
|
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