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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | DNA polymerase beta | ||
| Ligand | BDBM50027117 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEBML_50773 | ||
| IC50 | 370000±n/a nM | ||
| Citation |  Wu, RS; Wolpert-DeFilippes, MK; Quinn, FR Quantitative structure--activity correlations of rifamycins as inhibitors of viral RNA-directed DNA polymerase and mammalian alpha and beta DNA polymerases. J Med Chem23:256-61 (1980) [PubMed] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| DNA polymerase beta | |||
| Name: | DNA polymerase beta | ||
| Synonyms: | DPOLB_MOUSE | Polb | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 38297.87 | ||
| Organism: | Mus musculus | ||
| Description: | ChEMBL_50773 | ||
| Residue: | 335 | ||
| Sequence: |
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| BDBM50027117 | |||
| n/a | |||
| Name | BDBM50027117 | ||
| Synonyms: | 2,15,17,26,29-pentahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-6,23-dioxo-8,30-dioxa-24-azatetracyclo[23.3.1.14,7.05,28]triaconta-1(28),2,4,9,19,21,25(29),26-octaen-13-yl acetate | CHEMBL86846 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C37H47NO12 | ||
| Mol. Mass. | 697.7686 | ||
| SMILES | COC1\C=C\OC2(C)Oc3c(C2=O)c2cc(O)c(NC(=O)\C(C)=C/C=C/C(C)C(O)C(C)C(O)C(C)C(OC(C)=O)C1C)c(O)c2c(O)c3C |c:23,t:3,25| | ||
| Structure | 
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