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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | DNA polymerase beta | ||
| Ligand | BDBM50027130 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEBML_50773 | ||
| IC50 | 13000±n/a nM | ||
| Citation |  Wu, RS; Wolpert-DeFilippes, MK; Quinn, FR Quantitative structure--activity correlations of rifamycins as inhibitors of viral RNA-directed DNA polymerase and mammalian alpha and beta DNA polymerases. J Med Chem23:256-61 (1980) [PubMed] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| DNA polymerase beta | |||
| Name: | DNA polymerase beta | ||
| Synonyms: | DPOLB_MOUSE | Polb | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 38297.87 | ||
| Organism: | Mus musculus | ||
| Description: | ChEMBL_50773 | ||
| Residue: | 335 | ||
| Sequence: |
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| BDBM50027130 | |||
| n/a | |||
| Name | BDBM50027130 | ||
| Synonyms: | 2,15,17,29-tetrahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-26-carbaldehyde O-octyl-oxime-6,23-dioxo-8,30-dioxa-24-azatetracyclo[23.3.1.14,7.05,28]triaconta-1(28),2,4,9,19,21,25(29),26-octaen-13-yl acetate | CHEMBL82619 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C46H64N2O12 | ||
| Mol. Mass. | 837.0066 | ||
| SMILES | CCCCCCCCO\N=C\c1cc2c3C(=O)C4(C)Oc3c(C)c(O)c2c(O)c1NC(=O)\C(C)=C/C=C/C(C)C(O)C(C)C(O)C(C)C(OC(C)=O)C(C)C(OC)\C=C\O4 |c:36,t:38,60| | ||
| Structure | 
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