| Reaction Details |
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 | Report a problem with these data |
| Target | Thymidine kinase, cytosolic |
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| Ligand | BDBM50027352 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_207844 (CHEMBL810053) |
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| Ki | 2000±n/a nM |
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| Citation |  Schroeder, AC; Bardos, TJ; Cheng, YC Synthesis and antiviral activity of 1-(2-deoxy-beta-D-ribofuranosyl)-5-(methylmercapto)-2-pyrimidinone. J Med Chem24:109-12 (1981) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Thymidine kinase, cytosolic |
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| Name: | Thymidine kinase, cytosolic |
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| Synonyms: | KITH_HUMAN | TK1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 25476.50 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1333884 |
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| Residue: | 234 |
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| Sequence: | MSCINLPTVLPGSPSKTRGQIQVILGPMFSGKSTELMRRVRRFQIAQYKCLVIKYAKDTR
YSSSFCTHDRNTMEALPACLLRDVAQEALGVAVIGIDEGQFFPDIVEFCEAMANAGKTVI
VAALDGTFQRKPFGAILNLVPLAESVVKLTAVCMECFREAAYTKRLGTEKEVEVIGGADK
YHSVCRLCYFKKASGQPAGPDNKENCPVPGKPGEAVAARKLFAPQQILQCSPAN
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|
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| BDBM50027352 |
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| n/a |
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| Name | BDBM50027352 |
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| Synonyms: | 1-(4,5-Dihydroxy-tetrahydro-furan-2-yl)-5-methylsulfanyl-1H-pyrimidin-2-one | CHEMBL268232 |
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| Type | Small organic molecule |
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| Emp. Form. | C9H12N2O4S |
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| Mol. Mass. | 244.268 |
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| SMILES | CSc1cnc(=O)n(c1)C1CC(O)C(O)O1 |
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| Structure | 
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