Reaction Details |
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Target | Pepsin A |
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Ligand | BDBM50027909 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEBML_154017 |
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Ki | 1.5±n/a nM |
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Citation | Rich, DH; Salituro, FG Synthesis of analogues of pepstatin. Effect of structure in subsites P1', P2', and P2 on inhibition of porcine pepsin. J Med Chem26:904-10 (1983) [PubMed] |
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More Info.: | Get all data from this article, Assay Method |
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Pepsin A |
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Name: | Pepsin A |
Synonyms: | PEPA_PIG | PGA | Pepsin | Pepsin A precursor |
Type: | Enzyme |
Mol. Mass.: | 41232.87 |
Organism: | Porcine |
Description: | n/a |
Residue: | 385 |
Sequence: | MKWLLLLSLVVLSECLVKVPLVRKKSLRQNLIKNGKLKDFLKTHKHNPASKYFPEAAALI
GDEPLENYLDTEYFGTIGIGTPAQDFTVIFDTGSSNLWVPSVYCSSLACSDHNQFNPDDS
STFEATSQELSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDGIL
GLAYPSISASGATPVFDNLWDQGLVSQDLFSVYLSSNDDSGSVVLLGGIDSSYYTGSLNW
VPVSVEGYWQITLDSITMDGETIACSGGCQAIVDTGTSLLTGPTSAIANIQSDIGASENS
DGEMVISCSSIDSLPDIVFTINGVQYPLSPSAYILQDDDSCTSGFEGMDVPTSSGELWIL
GDVFIRQYYTVFDRANNKVGLAPVA
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BDBM50027909 |
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n/a |
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Name | BDBM50027909 |
Synonyms: | 2-(2-{3-Hydroxy-6-methyl-4-[3-methyl-2-(3-methyl-butyrylamino)-butyrylamino]-heptanoylamino}-propionylamino)-3-phenyl-propionic acid methyl ester | CHEMBL352982 |
Type | Small organic molecule |
Emp. Form. | C31H50N4O7 |
Mol. Mass. | 590.7513 |
SMILES | COC(=O)C(Cc1ccccc1)NC(=O)C(C)NC(=O)CC(O)C(CC(C)C)NC(=O)C(NC(=O)CC(C)C)C(C)C |
Structure |
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